DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32085 and Fbxl16

DIOPT Version :10

Sequence 1:NP_729732.1 Gene:CG32085 / 39311 FlyBaseID:FBgn0052085 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_001366323.1 Gene:Fbxl16 / 214931 MGIID:2448488 Length:575 Species:Mus musculus


Alignment Length:553 Identity:270/553 - (48%)
Similarity:358/553 - (64%) Gaps:55/553 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   157 QSQQQHLQLQASTLINSNHHVMVGPAPPTGMPL-----GAPPTPT------------VKSIAKQM 204
            ||:|.|:...||......|...:  ||.|.:.|     |:||...            ::..|::|
Mouse    35 QSKQGHIGPVASAQDPEPHCQPL--APRTAILLSWQDSGSPPLCADGTLEAALRPRGLRERARKM 97

  Fly   205 NITIPGGGVNPGSPTFSTMGMVA------AQKAAASAGGTPLQLRK--------QLPNPHLHHPY 255
              :.||...:|..|.....|:|.      ...||:...|||....:        .||.|.|..|.
Mouse    98 --SSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPAAKNRPCQPPPPPTLPPPSLATPL 160

  Fly   256 GSMGI---------NAASPLIMQHQLHPPPIHSIEQLMLDDRFLSRFFQYFSPYERRILAQVCIK 311
            ..:.:         ..||..:....:..||      |..|::.|:..|.|||..|:.||||||..
Mouse   161 SRVALAGGPCPPASGPASGPVSGPPVERPP------LATDEKILNGLFWYFSACEKCILAQVCKA 219

  Fly   312 WRDTLYRSPRYWSGLLPTLQCREL-RQMPGCDRGKLYN--SLIRRGFHALGLVGASDEDALDVVH 373
            ||..||: |::|:||.|.|..:|| ..:||.:: :..|  ....|||....|||.||.|..:.:.
Mouse   220 WRRVLYQ-PKFWAGLTPVLHAKELYNVLPGGEK-EFVNLQGFAARGFEGFCLVGVSDLDICEFID 282

  Fly   374 SFPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELAGCNEVTEAGLWACLTPRIVSLSLAD 438
            ::.|:.|.|.::||:.|:|:|.|||.:|:.:|.:..|||:|||:.||||||:.|:.||.|||::|
Mouse   283 NYSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSD 347

  Fly   439 CINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIVNIV 503
            |||:||:|:.|::||||:|.|.|||||||||.||.||:.:|.||...|||.||||:||||:||:|
Mouse   348 CINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVV 412

  Fly   504 HSLPHLTVLSLSGCSKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLEELTLDR 568
            ||||:||.||||||||:|||||||:||||:|||:|||||||||||.:|||:||||::||||.|||
Mouse   413 HSLPNLTSLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDR 477

  Fly   569 CVHITDIGVGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSSGLSSLIQL 633
            ||.|||.|:.|:|||.||.:|:||||.||:||||:||.:||||::||||||||||::|||.|:||
Mouse   478 CVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAMRNLRLLSLAGCPLLTTTGLSGLVQL 542

  Fly   634 RHLQELELTNCPGASHELFDYLKEHLPRCLIIE 666
            :.|:||||||||||:.|||.|..:||||||:||
Mouse   543 QELEELELTNCPGATPELFKYFSQHLPRCLVIE 575

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32085NP_729732.1 F-box_FBXL16 283..325 CDD:438899 20/41 (49%)
leucine-rich repeat 382..406 CDD:275381 10/23 (43%)
AMN1 383..600 CDD:187754 144/216 (67%)
leucine-rich repeat 431..456 CDD:275381 15/24 (63%)
leucine-rich repeat 457..482 CDD:275381 16/24 (67%)
leucine-rich repeat 483..508 CDD:275381 17/24 (71%)
leucine-rich repeat 509..534 CDD:275381 21/24 (88%)
leucine-rich repeat 535..560 CDD:275381 20/24 (83%)
leucine-rich repeat 561..585 CDD:275381 17/23 (74%)
leucine-rich repeat 586..610 CDD:275381 15/23 (65%)
leucine-rich repeat 636..661 CDD:275381 17/24 (71%)
Fbxl16NP_001366323.1 PHA03247 <31..193 CDD:223021 37/167 (22%)
F-box_FBXL16 191..232 CDD:438899 20/41 (49%)
AMN1 297..509 CDD:187754 142/211 (67%)
leucine-rich repeat 316..339 CDD:275381 13/22 (59%)
leucine-rich repeat 340..365 CDD:275381 15/24 (63%)
leucine-rich repeat 366..391 CDD:275381 16/24 (67%)
leucine-rich repeat 392..417 CDD:275381 17/24 (71%)
leucine-rich repeat 418..443 CDD:275381 21/24 (88%)
leucine-rich repeat 444..469 CDD:275381 20/24 (83%)
leucine-rich repeat 470..494 CDD:275381 17/23 (74%)
leucine-rich repeat 495..514 CDD:275381 12/18 (67%)

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