DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and K05C4.9

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001362175.1	Gene:	K05C4.9 / 187021	WormBaseID:	WBGene00010585	Length:	718	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	48/218 - (22%)
Similarity:	81/218 - (37%)	Gaps:	75/218 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   496 NHGIVNIVHSLPHLTVLSLSGCSKLTDDGVELIAENLQK----------------------LRAL 538
            |..::.:..|.|.|.||.:||.:..:..|:..: :|||:                      |:.|
Worm   164 NDELLRLCVSFPSLCVLDISGTNIASLHGLSNL-KNLQELSIRYLEFANANNLVDLFQLTNLKVL 227

  Fly   539 DLSWCPRITDAS--LEYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTALFLRWCSQVRDFG 601
            |:|....:..:.  |.::.|.:| |.||.:..|.. |||.....:.:||.
Worm   228 DMSKSKNLETSKNVLRFVECGMN-LPELRVLDCSG-TDIDEELFAKLLSF--------------- 275

  Fly   602 LQHLCSMRNLQVLSLAGCPL-----------LTSSGLSSLIQ-LRHLQELE----LTNCPGASHE 650
                  :.|||.::|..|.|           |.|:.|.:..| |.:..:|:    :..|   ..:
Worm   276 ------LPNLQQIALMDCQLKHAVFSTEIRVLNSATLETSFQTLNYYSKLKKSDSVMKC---FQD 331

  Fly   651 LFDYLKEH--------LPRCLII 665
            :|..|||:        :..||.|
Worm   332 IFFLLKEYYTQNKEYDIAGCLAI 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381
		AMN1	383..600	CDD:187754	28/127 (22%)
		leucine-rich repeat	431..456	CDD:275381
		leucine-rich repeat	457..482	CDD:275381
		leucine-rich repeat	483..508	CDD:275381	2/11 (18%)
		leucine-rich repeat	509..534	CDD:275381	8/24 (33%)
		leucine-rich repeat	535..560	CDD:275381	6/26 (23%)
		leucine-rich repeat	561..585	CDD:275381	7/23 (30%)
		leucine-rich repeat	586..610	CDD:275381	0/23 (0%)
		leucine-rich repeat	636..661	CDD:275381	6/36 (17%)
K05C4.9	NP_001362175.1	leucine-rich repeat	126..151	CDD:275381
		leucine-rich repeat	152..176	CDD:275381	2/11 (18%)
		leucine-rich repeat	177..198	CDD:275378	6/21 (29%)
		leucine-rich repeat	199..223	CDD:275378	2/23 (9%)
		leucine-rich repeat	224..253	CDD:275378	8/29 (28%)
		leucine-rich repeat	254..278	CDD:275378	7/45 (16%)
		leucine-rich repeat	279..290	CDD:275378	4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162711
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930