DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and H24K24.2

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001300124.1	Gene:	H24K24.2 / 186774	WormBaseID:	WBGene00019239	Length:	473	Species:	Caenorhabditis elegans

Alignment Length:	306	Identity:	73/306 - (23%)
Similarity:	111/306 - (36%)	Gaps:	66/306 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 LFELELAGCNE-VTEAGLWACLTPRIVSLSLADCIN--IADEAVGAV-AQLLPSLYEFSL----- 462
            |.:|:...|.| :|..|.:.|       |...|..|  ::.|.|.|: .|.|.||...:|
Worm    41 LMKLKFGLCEEALTRFGHFFC-------LKKVDLFNYHVSKELVEAIRCQNLESLSLGNLDWVKR 98

  Fly   463 -----QAYHVT---DAALGYFSPKQSHSLSILRLQSCWELTNHGIVNIVHSLPHLTVLSLSGCSK 519
                 ..|.:.   ::.|...|....|||.| .::|  .........|.:.||.|...:::|  :
Worm    99 GRRFMNGYDIVRFLESFLNEESRNVLHSLEI-TMES--PFAKEWPAKINNMLPALKCFAING--Q 158

  Fly   520 LTDDGVELIAENLQKLRALDLSWCPRITDAS-------LEYIA---CDLNQLEEL---------- 564
            :.||....:......||.||:| ...|.:.|       |:.::   .|:||..:|
Worm   159 VNDDEFSHLCIGFSNLRVLDIS-NTNIRNLSGMKMLVNLQILSMRNLDINQTSDLIELFSLTKLT 222

  Fly   565 TLDRCVHITDIGVGYISTMLSLTALFLRW----CSQV---RDFGLQHLCSMRNLQVLSLAGCPLL 622
            .||......:.|...|||.|....:.|..    ||:.   |:|....|.|..::..:|..||.|.
Worm   223 VLDVSQDKQNSGTKIISTYLECRKILLDLKFIDCSRTDINREFAKTLLSSHPSIVHVSAIGCDLK 287

  Fly   623 TSSGLSSLIQLRHLQELELTNCPGASHELFDY--LKEHLPRCLIIE 666
            ..|...:.|       ...|:.......|.|:  ||..|..|..:|
Worm   288 NFSKCGTRI-------FYCTSIESLFRSLIDFTNLKNELATCRCLE 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381
		AMN1	383..600	CDD:187754	56/236 (24%)
		leucine-rich repeat	431..456	CDD:275381	8/27 (30%)
		leucine-rich repeat	457..482	CDD:275381	5/37 (14%)
		leucine-rich repeat	483..508	CDD:275381	5/24 (21%)
		leucine-rich repeat	509..534	CDD:275381	4/24 (17%)
		leucine-rich repeat	535..560	CDD:275381	9/34 (26%)
		leucine-rich repeat	561..585	CDD:275381	7/33 (21%)
		leucine-rich repeat	586..610	CDD:275381	7/30 (23%)
		leucine-rich repeat	636..661	CDD:275381	6/26 (23%)
H24K24.2	NP_001300124.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162706
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930