DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and F44E5.2

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_496512.2	Gene:	F44E5.2 / 185735	WormBaseID:	WBGene00009689	Length:	489	Species:	Caenorhabditis elegans

Alignment Length:	296	Identity:	61/296 - (20%)
Similarity:	121/296 - (40%)	Gaps:	70/296 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 LRCSSISDRGLETLLDHLQ-----SLFELELAGCNEV--------TEAGLWACL-TPRIVSLSLA 437
            :.|.|:||..:..:..::|     |.|..|::  |::        .|.....|| ..|.::::.|
Worm     1 MACKSLSDISVGQVAKNIQHRDYDSCFNPEIS--NQIFTKLVALDIELDPNYCLQISRKLNITKA 63

  Fly   438 DCINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIVNI 502
            .|.|:..|.:    :||.:....||...::......|...|::..::|.||          :.::
Worm    64 VCKNVTTEHI----KLLSNNCILSLTIGNIDKVKQVYQDDKENPIINIARL----------LEDV 114

  Fly   503 V--HSLPHLTVLSLSGCSKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLEELT 565
            :  .|..:|..|.:.|....:.:..:.:...|..|:.|.:  |.|      .:|..:.:||
Worm   115 LGEESRQNLQYLDIQGNELFSYNWPKALGHMLPSLQTLIV--CQR------SFINDEFSQL---- 167

  Fly   566 LDRC--------VHITDIGVGYISTMLSLTALFLRWCSQVRDF----GLQHLCSMRNLQVLSLAG 618
               |        :.|:|..:|.:|.:.:|..| .:.|....:|    .::.|..:::|:||:::.
Worm   168 ---CNSFPNLHKLDISDTNIGNLSGISNLKNL-QKLCMMNLEFESYDDIKELFEVKSLRVLNISR 228

  Fly   619 -----CPLLTSSGLSSLIQLRH-LQELELTNCPGAS 648
                 .|.|    :...|||:. |.||...:|.|.:
Worm   229 DRKDFKPSL----IMQYIQLKEVLPELRFLDCSGTN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381	5/23 (22%)
		AMN1	383..600	CDD:187754	46/236 (19%)
		leucine-rich repeat	431..456	CDD:275381	6/24 (25%)
		leucine-rich repeat	457..482	CDD:275381	4/24 (17%)
		leucine-rich repeat	483..508	CDD:275381	4/26 (15%)
		leucine-rich repeat	509..534	CDD:275381	4/24 (17%)
		leucine-rich repeat	535..560	CDD:275381	5/24 (21%)
		leucine-rich repeat	561..585	CDD:275381	6/31 (19%)
		leucine-rich repeat	586..610	CDD:275381	5/27 (19%)
		leucine-rich repeat	636..661	CDD:275381	5/13 (38%)
F44E5.2	NP_496512.2	leucine-rich repeat	123..148	CDD:275380	4/24 (17%)
		leucine-rich repeat	149..173	CDD:275380	8/38 (21%)
		LRR_4	172..215	CDD:289563	8/43 (19%)
		leucine-rich repeat	174..195	CDD:275380	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162707
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930