DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32085 and skpt-1

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_741137.1	Gene:	skpt-1 / 175749	WormBaseID:	WBGene00018613	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	242	Identity:	63/242 - (26%)
Similarity:	97/242 - (40%)	Gaps:	48/242 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   418 VTEAGLWACLTPRIVSLSL----ADCINIADEAVGAVAQLLPSLYE-FSLQAYHVTDAALGYFSP 477
            ::|..|.|....:|..|.|    ||.|..|||.:..||.|..|..| ..|...::| |.......
Worm   140 ISEISLIALSQRKIKVLRLAGAKADRILRADERLVEVALLSTSRLELLDLSRTNLT-ARQMQIML 203

  Fly   478 KQSHSLSILRLQSCWELTNHGIVNIVHSLPHLTVLSLSGCSKLTDDGVELIAENLQKLRALDLSW 542
            |....|..|.::.. :|.:|..:.|..: ..|..|.:|..:.:|.:|..||..|.:.|:.|:|:|
Worm   204 KPCQKLKCLSIEGN-QLDDHVAICIAEN-RGLRELDISMTNGITANGASLIFRNCKDLQQLNLAW 266

  Fly   543 C----PRIT-------------------------DASLEYIACDLNQLEELTLDRCVHITDIGVG 578
            |    |.:|                         :..:|.:|...|.:.:|.|...|.|:|.|:.
Worm   267 CGLTQPIVTVIIHSIGEKLKKLNLSGTVRNFGINNKHIEILAAKSNYVTDLDLSDNVEISDPGLA 331

  Fly   579 YI-STMLSLTALFLRWCSQVRDFGLQ-----HLCSMRNLQVLSLAGC 619
            .| :....||.:.|..|     :||.     |..|..:|..|::.||
Worm   332 VILNKFPRLTTISLNRC-----YGLDPNMVVHFNSKPSLVYLNVHGC 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381
		AMN1	383..600	CDD:187754	55/216 (25%)
		leucine-rich repeat	431..456	CDD:275381	12/28 (43%)
		leucine-rich repeat	457..482	CDD:275381	5/25 (20%)
		leucine-rich repeat	483..508	CDD:275381	5/24 (21%)
		leucine-rich repeat	509..534	CDD:275381	8/24 (33%)
		leucine-rich repeat	535..560	CDD:275381	9/53 (17%)
		leucine-rich repeat	561..585	CDD:275381	7/24 (29%)
		leucine-rich repeat	586..610	CDD:275381	8/28 (29%)
		leucine-rich repeat	636..661	CDD:275381
skpt-1	NP_741137.1	F-box-like	92..130	CDD:372399
		AMN1	150..373	CDD:187754	58/230 (25%)
		leucine-rich repeat	153..183	CDD:275381	12/29 (41%)
		leucine-rich repeat	184..208	CDD:275381	5/24 (21%)
		leucine-rich repeat	209..232	CDD:275381	5/24 (21%)
		leucine-rich repeat	233..258	CDD:275381	8/24 (33%)
		leucine-rich repeat	259..284	CDD:275381	7/24 (29%)
		leucine-rich repeat	285..313	CDD:275381	2/27 (7%)
		leucine-rich repeat	314..339	CDD:275381	7/24 (29%)
		leucine-rich repeat	340..362	CDD:275381	7/26 (27%)
		leucine-rich repeat	365..388	CDD:275381	4/9 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162699
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840