DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and gadr-6

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_493455.1	Gene:	gadr-6 / 173273	WormBaseID:	WBGene00009823	Length:	710	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	47/233 - (20%)
Similarity:	77/233 - (33%)	Gaps:	94/233 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   446 AVGAVAQLL------PSLYEFSLQAYHVTDAALGYFSPKQSHSLSILRL---------------- 488
            |..|:|:|:      ...|.|..::.:...|.|....|:.|:::. |:|
Worm     9 AAAAIAKLIHNGHFNSKSYAFDQESSNEVYAQLLRLDPQWSYNID-LKLKGLSFILTKVNFENVE 72

  Fly   489 ---QSCWELTNHGIVNIV-------HSLPH----------LTVLSLSGCSKLTDDGVELIAENLQ 533
               |:...||.|.:.::|       .||.|          :..|.|||.|:.:...::...:.|.
Worm    73 MGPQTFGLLTQHNLKSLVLGNQDEIPSLEHYMSRLFRTSQIDHLDLSGRSQFSTAWLKTTGQQLP 137

  Fly   534 KLRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTALFLRWCSQVR 598
            .||.|::|                                  ||..      |...|.::|.
Worm   138 LLRTLNVS----------------------------------GVKL------LNPDFFQFCK--- 159

  Fly   599 DFGLQHLCSMRNLQVLSLAGCPLLTSSGLSSLIQLRHL 636
                    |..||..|.::.|.:...:|:|.|..||||
Worm   160 --------SFPNLYSLDISNCGVTILTGISRLKNLRHL 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381
		AMN1	383..600	CDD:187754	35/195 (18%)
		leucine-rich repeat	431..456	CDD:275381	4/15 (27%)
		leucine-rich repeat	457..482	CDD:275381	6/24 (25%)
		leucine-rich repeat	483..508	CDD:275381	9/50 (18%)
		leucine-rich repeat	509..534	CDD:275381	6/24 (25%)
		leucine-rich repeat	535..560	CDD:275381	4/24 (17%)
		leucine-rich repeat	561..585	CDD:275381	2/23 (9%)
		leucine-rich repeat	586..610	CDD:275381	4/23 (17%)
		leucine-rich repeat	636..661	CDD:275381	1/1 (100%)
gadr-6	NP_493455.1	leucine-rich repeat	86..112	CDD:275381	4/25 (16%)
		leucine-rich repeat	113..138	CDD:275381	6/24 (25%)
		leucine-rich repeat	139..163	CDD:275381	10/74 (14%)
		leucine-rich repeat	164..185	CDD:275381	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162713
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930