Protein Alignment CG32085 and FBXO39

DIOPT Version :9

• Sequence 1: NP_729732.1
• Gene: CG32085 / 39311
• FlyBaseID: FBgn0052085
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_694962.1
• Gene: FBXO39 / 162517
• HGNCID: 28565
• Length: 442
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 93/431 - (21%)
• Similarity: 144/431 - (33%)
• Gaps: 156/431 - (36%)

  Fly   285 LDDRFLSRFFQYFSPYERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELRQMPGCDRGKLYNS 349
            |.|..|.|.|.:....:|...|.||.||...:| |...|.....|...|..|
Human    19 LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMY-SAELWRYRTITFSGRPSR------------- 69

  Fly   350 LIRRGFHALGLVGASD-EDALDVVHSFPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELA 413
                       |.||: |.|:..|..|                  .|.||.|.....:.:...|.
Human    70 -----------VHASEVESAVWYVKKF------------------GRYLEHLEVKFMNPYNAVLT 105

  Fly   414 GCNEVTEAGLWACLTP---RIVSLSLADCINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYF 475
            ...:||..||.:||:.   |:.|||:            ...:|...::..|:::..:  ::|.:|
Human   106 KKFQVTMRGLLSCLSKSNNRLKSLSI------------QYLELDRLVWRNSIRSSFI--SSLSFF 156

  Fly   476 SPKQSHSLSILRL--------QSCWEL------TNHGIV---NI---------VHSLP------- 507
            ..|....|..|.|        |.|..|      .|..::   ||         |::.|
Human   157 LKKMGKRLDYLNLKGARLTVEQGCQILDSLSYMRNENVISELNIEDYFSHHLAVYNSPQFKKTMS 221

  Fly   508 ---HLTVLSLS-GCSKLTDDGVELIAENLQKLRALD---------------LSWCP---RITDAS 550
               :|..|:|: .|  ::|:.:|.:.||...||.::               :||..   :.|:..
Human   222 TFHNLVSLNLNYNC--ISDELLENLCENASTLRTINIKCHVHDPHGQVIWGMSWAKLARQATNLK 284

  Fly   551 LEYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLS 615
            :.:....:.:.|.|..   :.:.:|.:..||         ||.|     :.....||||
Human   285 VNFFFERIMKYERLAR---ILLQEIPIRSIS---------LRSC-----YFSDPDCSMR------ 326

  Fly   616 LAGCPLLTSSGLSSLIQLRH-LQEL--ELTNCPGASHELFD 653
                |.|    :..|...|| ||:|  |..|    :||..|
Human   327 ----PTL----IDLLPTFRHTLQKLTCEFNN----NHESLD 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381	4/23 (17%)
		AMN1	383..600	CDD:187754	52/274 (19%)
		leucine-rich repeat	431..456	CDD:275381	4/24 (17%)
		leucine-rich repeat	457..482	CDD:275381	4/24 (17%)
		leucine-rich repeat	483..508	CDD:275381	11/60 (18%)
		leucine-rich repeat	509..534	CDD:275381	8/25 (32%)
		leucine-rich repeat	535..560	CDD:275381	5/42 (12%)
		leucine-rich repeat	561..585	CDD:275381	5/23 (22%)
		leucine-rich repeat	586..610	CDD:275381	6/23 (26%)
		leucine-rich repeat	636..661	CDD:275381	8/20 (40%)
FBXO39	NP_694962.1	F-box-like	16..57	CDD:289689	13/38 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900