DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32085 and si:dkey-59l11.10

DIOPT Version :9

Sequence 1:	NP_729732.1	Gene:	CG32085 / 39311	FlyBaseID:	FBgn0052085	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_017211008.1	Gene:	si:dkey-59l11.10 / 108183670	ZFINID:	ZDB-GENE-120703-17	Length:	1028	Species:	Danio rerio

Alignment Length:	326	Identity:	93/326 - (28%)
Similarity:	129/326 - (39%)	Gaps:	72/326 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 LGLVGASDEDALDVVHSFPLASKHVHS-LS-LRCSSIS--DRGLETLLDHLQS-LFELELAGCNE 417
            |.|:...|:.....:..|..:.||... || ..||:||  ....|..||.|.| .|.....|...
Zfish   532 LCLLEVKDQTLAREIQEFVKSDKHSEEYLSPAHCSTISYMIEMSEEPLDELDSNKFNTSAEGRRR 596

  Fly   418 VTEAGLWACLTPRIVSLSLADCINIADEAVGAVAQLLPS----LYEFSLQAYHVTDAALGYFSP- 477
            :|.|       .|....:|....|:..|...:::..|.|    |.|..|...|:.|:.:...|.
Zfish   597 LTAA-------VRNCRRALLQWCNLTVECCESLSSALQSSNCVLRELDLSNNHLQDSGVKKLSDG 654

  Fly   478 -KQSH-SLSILRLQSCWELTNHGIVNIVHSLPHLTVLSLSGC---------SKLTDDGVELIAEN 531
             |..| .|..|||.:| :||    |....||.  :.|..|.|         :.|.|.||:.:::.
Zfish   655 LKSQHCKLDTLRLAAC-KLT----VQCCESLS--SALQSSNCVLRELDLSNNDLQDSGVKKLSDG 712

  Fly   532 LQ----KLRALDLSWCPRITDASLEYIACDLNQ----LEELTLDRCVHITDIGVGYISTMLSLTA 588
            |:    ||..|.|:.| .:|....|.::..|..    |.||.|.. .|:.|.||..:|..|.
Zfish   713 LKSQHCKLDTLRLAAC-NLTVECCESLSSALQSSNCVLRELDLSN-NHLQDSGVKKLSDGLK--- 772

  Fly   589 LFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSSG---LSSLIQLR--HLQELELT-NCPGA 647
                         .|| |   .|..|.|:|| ::|..|   |||.:...  ||:||:|: |.||.
Zfish   773 -------------SQH-C---KLDTLRLSGC-MVTEEGCGFLSSALTSNPSHLRELDLSYNHPGD 819

  Fly   648 S 648
            |
Zfish   820 S 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	leucine-rich repeat	382..406	CDD:275381	10/27 (37%)
		AMN1	383..600	CDD:187754	65/245 (27%)
		leucine-rich repeat	431..456	CDD:275381	4/24 (17%)
		leucine-rich repeat	457..482	CDD:275381	8/27 (30%)
		leucine-rich repeat	483..508	CDD:275381	10/24 (42%)
		leucine-rich repeat	509..534	CDD:275381	8/37 (22%)
		leucine-rich repeat	535..560	CDD:275381	7/24 (29%)
		leucine-rich repeat	561..585	CDD:275381	9/23 (39%)
		leucine-rich repeat	586..610	CDD:275381	3/23 (13%)
		leucine-rich repeat	636..661	CDD:275381	8/14 (57%)
si:dkey-59l11.10	XP_017211008.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010