Protein Alignment Polr3H and POLR3H

DIOPT Version :10

• Sequence 1: NP_648490.1
• Gene: Polr3H / 39310
• FlyBaseID: FBgn0036188
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: XP_054181193.1
• Gene: POLR3H / 171568
• HGNCID: 30349
• Length: 237
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 120/215 - (55%)
• Similarity: 155/215 - (72%)
• Gaps: 17/215 - (7%)

  Fly     1 MFVLAELKDNVRIAPDQFHLKLVDAVRDEIDRKLANKVLLNVGLCIALKDIVSLKDSIILPGDGA 65
            ||||.|:.|.|||.|.||..||.|::.:|:::||||||:.||||||.|.||..|:|:.:.|||||
Human    34 MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGA 98

  Fly    66 SHTEVLFRYVVFRPMVGTVITGKIRNCSREGVHVTLGFFDDILIPHAALQHPSRFDEAEQAWVWE 130
            |||:|.||.|||.|.:..::.|||:.||.|||||:||||||||||..:||.|::||||||.||||
Human    99 SHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWE 163

  Fly   131 YPLEDGAKHDLFMDVGEPIKFRVSREIFEETSPIGPPKTEAQTQQGASTSAAVASATSQEV---K 192
            |..|:|| |||:||.||.|:|||..|.|.:|||.||             |:|.|:.:|:|:   :
Human   164 YETEEGA-HDLYMDTGEEIRFRVVDESFVDTSPTGP-------------SSADATTSSEELPKKE 214

  Fly   193 TPYRIIGAINESGLGVLSWW 212
            .||.::|:|:|.|||:||||
Human   215 APYTLVGSISEPGLGLLSWW 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr3H	NP_648490.1	RNAP_III_Rpc25_N	2..81	CDD:239822	47/78 (60%)
		RNA_pol_Rbc25	84..212	CDD:400543	70/130 (54%)
POLR3H	XP_054181193.1	RNAP_III_Rpc25_N	35..114	CDD:239822	47/78 (60%)
		RNA_pol_Rbc25	116..234	CDD:400543	70/131 (53%)