Protein Alignment RIOK1 and Riok1

DIOPT Version :10

• Sequence 1: NP_648489.1
• Gene: RIOK1 / 39309
• FlyBaseID: FBgn0036187
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_077204.2
• Gene: Riok1 / 71340
• MGIID: 1918590
• Length: 567
• Species: Mus musculus
• Alignment Length: 582
• Identity: 272/582 - (46%)
• Similarity: 359/582 - (61%)
• Gaps: 45/582 - (7%)

  Fly    16 EDLRSSEWTNDFKNLTLKHEIFKDIKLTPKEDCDDLAQVIATANEEDEPEDEEPEEYDEDDYDDI 80
            :|..||:..|            |:::....||...|.:.:..|..|.:.:.|..|   |||||
Mouse    17 DDADSSDSEN------------KELQPIHAEDGGVLLKSLQNAAAEVKGDAETDE---EDDYD-- 64

  Fly    81 GDDYDTYEEAYTGFNKLHVQPQLTNAS--GGGSGGGAGGASGGSQRVSSYQPNEKLLRRYSARIN 143
             ||.|.|.:..||        :||...  .|||...|...:..........|.:|.||::..:||
Mouse    65 -DDDDWYLDDATG--------KLTKGCTWNGGSNYQANRQTSNYNSAKMSTPIDKSLRKFENKIN 120

  Fly   144 VEKYDPTTNMSAQAANRLVNFDRRDRTQVRDKHDRATAEQVMDPRTRMILFKLLNRGMIQEINGC 208
            :.|.:.|.:::.:...:| .....:..:::||.||||.|||:||||||||||||::..|.||:||
Mouse   121 LNKLNVTDSVTNKVTVKL-RQKEAESYRIKDKADRATVEQVLDPRTRMILFKLLHKDHISEIHGC 184

  Fly   209 ISTGKEANVYHAVSKNGEEEFAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKHNPRKMVRTWAEK 273
            ||||||||||:|.:.:||.. ||||||||||:||||||||:||||||.||||.||||||||||||
Mouse   185 ISTGKEANVYYASTPSGESR-AIKIYKTSILMFKDRDKYVTGEFRFRRGYCKGNPRKMVRTWAEK 248

  Fly   274 EMRNYLRMRNAGVPVPEPILLRSHVLVMRFCGRDGWPAPKLKDVELSTSKARELYRDCVVIMWRI 338
            ||||..|::.|.:|.||||.||||||:|.|.|:|..|||.||:|:||.|||||||...:..|.::
Mouse   249 EMRNLCRLKTANIPCPEPIRLRSHVLLMGFIGKDDMPAPLLKNVQLSESKARELYLQVIQYMRKM 313

  Fly   339 YNQCRLVHADLSEFNILLQDGQLVIIDVSQSVEHDHPHSFDFLRKDCTNISEFFRKRAVATMTVK 403
            |...|||||||||||:|...|.:.||||||||||||||:.:||||||||:::||.|.|||.|||:
Mouse   314 YQDARLVHADLSEFNMLYHGGDVYIIDVSQSVEHDHPHALEFLRKDCTNVNDFFSKHAVAVMTVR 378

  Fly   404 ELFDFITDQTITTENMEECLERISERIKDRDFDAISAQEKIDEAVWQNTYIPKRLDEVRHFERDV 468
            |||||:||.:||.:||:..||:..|....|..:..::|:.:||.|::..|||:.|:||:::||||
Mouse   379 ELFDFVTDPSITADNMDAYLEKAMEIASQRTKEEKTSQDHVDEEVFKQAYIPRTLNEVKNYERDV 443

  Fly   469 ---------AKAKQGVQQNLIYGKITGLTSDLDVQQKPDVLQSSTAKEDDGSEAQTSGSEDEDNS 524
                     ..|....|.|::|..:.||..||...||...|..|..||:     ...||:|...|
Mouse   444 DIMMRLKEEDMALNTQQDNILYQTVMGLKKDLSGVQKVPALLESEVKEE-----TCFGSDDAGGS 503

  Fly   525 QDNDNDEDAKKFKNSARPREESPE-SKKARKKAVKDAKAEQRKVKVKKHVKKRKEKMGSMKK 585
            :.:|...:.::.:...|.....|: .||.|||.||:|:.|:||.|:.|||||||||....||
Mouse   504 ECSDTVSEEQEDQAGCRNHIADPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKAKK 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RIOK1	NP_648489.1	RIO1_euk	205..395	CDD:270698	131/189 (69%)
Riok1	NP_077204.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		7/32 (22%)
		RIO1_euk	181..370	CDD:270698	131/189 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	495..567		30/71 (42%)