Protein Alignment RIOK1 and riok1

DIOPT Version :10

• Sequence 1: NP_648489.1
• Gene: RIOK1 / 39309
• FlyBaseID: FBgn0036187
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_998160.1
• Gene: riok1 / 406268
• ZFINID: ZDB-GENE-040426-1927
• Length: 552
• Species: Danio rerio
• Alignment Length: 595
• Identity: 275/595 - (46%)
• Similarity: 373/595 - (62%)
• Gaps: 68/595 - (11%)

  Fly     7 KYSDAEEDEEDLRSSEWTNDFKNLTLKHEIFKDIKLTP-KEDCDDLAQVIATANEEDEPEDEEPE 70
            ::.||:|.|.                        .::| |...::....:...:.|:..:.|..|
Zfish     8 QFDDADESES------------------------VISPEKPSLENRLDEVTLQSVENNKQKENEE 48

  Fly    71 EYDEDDYDDIGDD--YDTYEEAYTGFNKLHVQPQLTNASGGGSGGGAGGASGGSQRVSSYQPNEK 133
            :||||:.||..||  :|..|.|...|.|.:      .|...|....|...:..::.:....|::|
Zfish    49 DYDEDEEDDDDDDDEWDWNESAGGDFTKRY------TAMRTGCNPQANRQNSNNKSIKMSTPSDK 107

  Fly   134 LLRRYSARINVEKYDPTTNMSAQAANRLVNFDRR---DRTQVRDKHDRATAEQVMDPRTRMILFK 195
            :||::..:||::|    .:.:....|::....::   |..:|:||.||||.|||:||||||||||
Zfish   108 VLRKFENKINLDK----LSYADSVINKVTVMQKQREADTFRVKDKSDRATVEQVLDPRTRMILFK 168

  Fly   196 LLNRGMIQEINGCISTGKEANVYHAVSKNGEEEFAIKIYKTSILVFKDRDKYVSGEFRFRHGYCK 260
            :|:||:..:||||||||||||||||.:..||.. ||||||||||:||||||||||||||||||||
Zfish   169 MLSRGVFSQINGCISTGKEANVYHATTAKGESR-AIKIYKTSILLFKDRDKYVSGEFRFRHGYCK 232

  Fly   261 HNPRKMVRTWAEKEMRNYLRMRNAGVPVPEPILLRSHVLVMRFCGRDGWPAPKLKDVELSTSKAR 325
            .||||||||||||||||.:|::.|.:|.||||:||||||||.|.|||..|||.||:..||.||||
Zfish   233 GNPRKMVRTWAEKEMRNLIRLQTAQIPSPEPIMLRSHVLVMSFIGRDDTPAPLLKNAVLSESKAR 297

  Fly   326 ELYRDCVVIMWRIYNQCRLVHADLSEFNILLQDGQLVIIDVSQSVEHDHPHSFDFLRKDCTNISE 390
            |||...:..|..:|::.|||||||||:|:|..:|:..||||||||||||||:.:||||||:|:::
Zfish   298 ELYLQIIQNMRIMYSEARLVHADLSEYNMLYHNGEAYIIDVSQSVEHDHPHALEFLRKDCSNVND 362

  Fly   391 FFRKRAVATMTVKELFDFITDQTITTENMEECLERISERIKDRDFDAISAQEKIDEAVWQNTYIP 455
            ||::..||.|||:|||:|:||.:|||:|:.:.|::..|...:|..:..|.|:|:||.|::..|||
Zfish   363 FFQRHNVAVMTVRELFEFVTDPSITTDNINQYLDKAMEIASERTAEERSDQDKVDEEVFKKAYIP 427

  Fly   456 KRLDEVRHFERDV---AKAKQGVQ------QNLIYGKITGLTSDLD-VQQKPDVLQSSTAKEDDG 510
            :.|:||.|:||||   .|.|:...      .|::|..:|||..||. ||..|.:|:.||..|..|
Zfish   428 RTLNEVTHYERDVDTMMKKKEDTSSEDTNTDNILYQTVTGLRKDLSGVQTVPSILEDSTKDESSG 492

  Fly   511 SEAQTSGSEDEDNSQDNDNDEDAKKFKNSARPREESPESKKARKKAVKDAKAEQRKVKVKKHVKK 575
            ||.:    ||||       ||:....:..|:|      .:|.:||.||:|:.|:||.||.|||||
Zfish   493 SEEE----EDED-------DEEKSGEETEAQP------DRKEQKKLVKEAQREKRKNKVPKHVKK 540

  Fly   576 RKEKMGSMKK 585
            ||||:...||
Zfish   541 RKEKVAKTKK 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RIOK1	NP_648489.1	RIO1_euk	205..395	CDD:270698	134/189 (71%)
riok1	NP_998160.1	RIO1_euk	178..367	CDD:270698	134/189 (71%)