Protein Alignment CG6071 and LAP2

DIOPT Version :9

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 766
• Identity: 137/766 - (17%)
• Similarity: 262/766 - (34%)
• Gaps: 251/766 - (32%)

  Fly    21 FVKPLRYN--LTILTR---LGSEDEQNQFEGIVSIDIEATQPTR---------------VIYLNS 65
            ::..||:.  ||:::|   :.:..:      ::.:.||..:|:|               .:....
Yeast    15 YLPTLRFRGLLTVISRNIHISTPHK------MLPLSIEQRRPSRSPEYDQSTLSNYKDFAVLHTD 73

  Fly    66 LNITISRQRTWIYRWASGRKIGALQIKRIIK----------KTSLIKI------------VIEL- 107
            ||:::|.:::.|    ||..  ..|:|::.:          .||.:.:            .||.
Yeast    74 LNLSVSFEKSAI----SGSV--TFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQIEQR 132

  Fly   108 --PLRS---------GEIYTLNMLFSGN--------LDRSQQYGYFAGYYDKTPRVFYSATRLEP 153
              ||.|         .:.:|||:.|...        |:..|..|       ..|.||   ::||.
Yeast   133 KEPLGSRLVINNASCNDNFTLNIQFRTTDKCTALQWLNSKQTKG-------GKPYVF---SQLEA 187

  Fly   154 DYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPV-----EEKPYKEIENYVSTTFMGSPPL 213
            .:|.::|||||.|..::.:..::.        |.:|.|     .|...|:...|   .|....|:
Yeast   188 IHARSLFPCFDTPSVKSTFTASIE--------SPLPVVFSGIRIEDTSKDTNIY---RFEQKVPI 241

  Fly   214 ATQQVMWTLHQLEKVYSGPAAAGENITVWSRP--------HLAEKLAKVPEMTPNLFSKYE---- 266
            ....:......|.....||.:     ||::.|        .....:.|..:....:..:||
Yeast   242 PAYLIGIASGDLSSAPIGPRS-----TVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTY 301

  Fly   267 ----TLFAYPLPKGADWGGKVDHVVLPRYTEMYSGQGIMVYGEDIVDSGQNGLESLQETLAELVA 327
                .:.:||      :||    :..|..|  ::...::.:....:|           .:|..:|
Yeast   302 DILVNVDSYP------YGG----MESPNMT--FATPTLIAHDRSNID-----------VIAHELA 343

  Fly   328 RQWNGLLVNLEDSDEEYVRNGINYYLSVQVM-AMDKEAYNTTHLS--------KTRLDVL----Y 379
            ..|:|.||.....:..::..|...||..::: |:..|.  |.|.|        :..:|.:    .
Yeast   344 HSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEP--TRHFSALIGWSDLQNSIDSMKDPER 406

  Fly   380 HDSLAKVKSIATDVKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELW 444
            ..:|.:..:..||..::......:|...||.|:..:..|...|...::.:||::|..|..:.:..
Yeast   407 FSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQFL 471

  Fly   445 EEFQRGARRSHQLPTGVSLPTVMESWMKQPGFP----LLTVQRDDAKQIVTITQSRYYQKYLDNS 505
            :..........::...|.    .|:|:.:||.|    .:|...|:..|:.            |.
Yeast   472 DTLYEFYPEKKEILDSVD----WETWLYKPGMPPRPHFITALADNVYQLA------------DK- 519

  Fly   506 SNDCWWVPVAYIVRNLTLPQVEWLGCQKNSRDILELSHIANPEDWLLINVDAAVPLRVFYDSYNL 570
                 ||.:|                          .|:...||:.  :...|:.::.| :|..|
Yeast   520 -----WVEMA--------------------------QHLKTTEDFR--SEFNAIDIKDF-NSNQL 550

  Fly   571 QLISEALRQ-----------DFTQIPELSR--IQLVDDALSLSWSGRLPYNV-TLNVISYLSNET 621
            .|..|.|.|           |:.:.|..||  :.:..|.:..|.:..:.:.: ...:.:.|..|.
Yeast   551 VLFLETLTQNGHSNKKPKDFDWAKFPVASRALLDIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEY 615

  Fly   622 SVLV-WETALLNLEKLQSIMRMTTGFRIFKLYMQKLIEPAFKTTLNSLSTK 671
            ..|. |         |.::.||            |.:.|.:: .|||:..:
Yeast   616 KHLADW---------LGTVGRM------------KFVRPGYR-LLNSVDRR 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	100/547 (18%)
		ERAP1_C	551..929	CDD:288671	26/136 (19%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	128/718 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810