DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6071 and AT1G63770

DIOPT Version :9

Sequence 1:	NP_648488.1	Gene:	CG6071 / 39308	FlyBaseID:	FBgn0036186	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001117543.4	Gene:	AT1G63770 / 842681	AraportID:	AT1G63770	Length:	987	Species:	Arabidopsis thaliana

Alignment Length:	1027	Identity:	178/1027 - (17%)
Similarity:	308/1027 - (29%)	Gaps:	350/1027 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLSAKLAESFVKPLRYNLTI--LTRLGSEDEQNQFEGIVSIDIE----ATQPTRVIYLNSLNITI 70
            |||.|:....:|...|.|..  || |.|...:..|  ::.||.|    .......:|.:|.|...
plant   153 LLSVKVEGKLLKEGDYQLDSRHLT-LPSLPAEESF--VLEIDTEIYPHKNTSLEGLYKSSGNFCT 214

  Fly    71 SRQRTWIYRWASG-RKIGALQIKRII--KKTSLI---KIVIELPLRSGEIYTLNMLFSGNLDRSQ 129
            ..:       |.| |||...|.:..|  |.|..:   |.:..:.|.:|     |::..|:::..:
plant   215 QCE-------AEGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNG-----NLISQGDIEGGR 267

  Fly   130 QYGYFAGYYDKTPRVF--------------------------YSATRLEPDYAHTVFPC-----F 163
            .|..:...:.|...:|                          ::.....|..||.::..     :
plant   268 HYALWEDPFKKPCYLFALVAGQLVSRDDTFTTRSGRQVSLKIWTPAEDLPKTAHAMYSLKAAMKW 332

  Fly   164 DDPRFRTPY-----NITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTFMGSPPLATQQVM---- 219
            |:..|...|     ||..|.|....|:.|         |.:..:.|...:.||..||....
plant   333 DEDVFGLEYDLDLFNIVAVPDFNMGAMEN---------KSLNIFNSKLVLASPETATDADYAAIL 388

  Fly   220 ----------WTLHQLEKVYSGPAAAGENITV--WSRPHLAEKLA--KVPEMTPNLFSK------ 264
                      ||              |..:|.  |.:..|.|.|.  :..|.:.::.|:
plant   389 GVIGHEYFHNWT--------------GNRVTCRDWFQLSLKEGLTVFRDQEFSSDMGSRTVKRIA 439

  Fly   265 -YETLFAYPLPKGADWGGKVDHVVLPR-YTEMYSGQGIMVYGEDIVDSGQNGLESLQETLAELVA 327
             ...|..|..|:.|   |.:.|.|.|. |.:|.:...:.||                       .
plant   440 DVSKLRIYQFPQDA---GPMAHPVRPHSYIKMDNFYTVTVY-----------------------E 478

  Fly   328 RQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHLSKTRLDVLYHDSLAKVKSIATD 392
            :.|             ...|.:..|...:|
plant   479 KVW-------------LFTNSVLLYAGAEV----------------------------------- 495

  Fly   393 VKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELWEEFQRGARRSHQL 457
                             :.|.|..||.:.|.||:..:|:|:...:.:.    |:|....|.::..
plant   496 -----------------VRMYKTLLGTQGFRKGIDLYFERHDEQAVTC----EDFFAAMRDANNA 539

  Fly   458 PTGVSLPTVMESWMKQPGFPLLTV---QRDDAKQIVTITQSRYYQKYLDNSSNDCWWVPVAYIV- 518
            .....|     .|..|.|.|::.|   ...||:.. ::..|:.........:.:..::||...:
plant   540 DFANFL-----QWYSQAGTPVVKVVSSYNADARTF-SLKFSQEIPPTPGQPTKEPTFIPVVVGLL 598

  Fly   519 ----RNLTLPQVEWLGCQKNSRDILELSHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALRQ 579
                :::||..|...|..:.......:..:...|:..   |.:.:|.|
plant   599 DSSGKDITLSSVHHDGTVQTISGSSTILRVTKKEEEF---VFSDIPER----------------- 643

  Fly   580 DFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNETSVLV----------WETALLNLE 634
               .:|.|.|                .::..:.|.:.|||:....:          ||...:...
plant   644 ---PVPSLFR----------------GFSAPVRVETDLSNDDLFFLLAHDSDEFNRWEAGQVLAR 689

  Fly   635 KLQSIMRMTTGFRIFKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTKSPVTTESSGTTESPDT 699
            ||  ::.:.:.|:..|   ...:.|.|...|.|:.:.:....|.   ....:|....|.......
plant   690 KL--MLNLVSDFQQNK---PLALNPKFVQGLGSVLSDSSLDKEF---IAKAITLPGEGEIMDMMA 746

  Fly   700 TESPDTAES-----PDTTESSNTTESPDTTESSDTTES-----PDTTKSDLSLSAILY------- 747
            ...||...:     .....|....|.....|::.:||:     .:..:..|..:|:.|
plant   747 VADPDAVHAVRKFVRKQLASELKEELLKIVENNRSTEAYVFDHSNMARRALKNTALAYLASLEDP 811

  Fly   748 ---RLAC-QFEIKECLTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRNGLEVHWIMVRDMFFE 808
               .||. ::::...||| |....||:.|.     |.:.|:.:|. ...|..:..:::|...|
plant   812 AYMELALNEYKMATNLTD-QFAALAALSQN-----PGKTRDDILA-DFYNKWQDDYLVVNKWF-- 867

  Fly   809 SENDKERSILLNSLS-CTTEYWAMQKLLSWALDSKKVPRTMTASLLSAVLRSPLGYYV----GKQ 868
                     ||.|.| .......::|||.......:.|..: .||:.....||:.::.    |.:
plant   868 ---------LLQSTSDIPGNVENVKKLLDHPAFDLRNPNKV-YSLIGGFCGSPVNFHAKDGSGYK 922

  Fly   869 FLIDHSKEILRSKDVKLILTPFINAMSTKAEFSALNDHLHRNLPSSMVSGLS 920
            ||.|...::                           |.|:..:.|.|||..|
plant   923 FLGDIVVQL---------------------------DKLNPQVASRMVSAFS 947

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	90/525 (17%)
CG6071	NP_648488.1	ERAP1_C	551..929	CDD:288671	71/406 (17%)
AT1G63770	NP_001117543.4	pepN	92..987	CDD:237585	178/1027 (17%)
AT1G63770	NP_001117543.4	M1_APN_1	103..985	CDD:189007	178/1027 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820