DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6071 and vrk3

DIOPT Version :9

Sequence 1:	NP_648488.1	Gene:	CG6071 / 39308	FlyBaseID:	FBgn0036186	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001037922.1	Gene:	vrk3 / 733538	XenbaseID:	XB-GENE-986614	Length:	511	Species:	Xenopus tropicalis

Alignment Length:	361	Identity:	72/361 - (19%)
Similarity:	121/361 - (33%)	Gaps:	109/361 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 NITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTFMGSPPLATQQVMWTLHQ---------LEKV 228
            |...|...|.|.:..:|          ||.:.|.        ||.|.|.|.:         |.|.
Frog   185 NSPKVRGVKSVKIELLP----------ENEILTD--------TQSVKWRLAEFLSAWNTGMLYKA 231

  Fly   229 YSGPAAAGE----------NITVWSRPHLAEKLAKVPEMTPNLFSKYETLFAYPLPKGADWGGKV 283
            |...:||.|          :..:::..:..::.||     .|:..|::...:.||....|..|..
Frog   232 YKTSSAAEEQHYIAKLDAKDGRIFTEQNFFQRAAK-----KNIVDKWKKSHSCPLIGIPDCVGFG 291

  Fly   284 DHVVLPRYTEMYS-------GQGIMVYGEDIVDSGQNG-----------------LESLQE---T 321
            .|       |.|.       ||.:    :.::|...:|                 ||.:.|   .
Frog   292 VH-------ESYRFLIFSALGQNL----QSVIDDDDDGKLPEKAIFHISYRIINTLEYIHENEYV 345

  Fly   322 LAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHLSKTRLDVLYHDSLAKV 386
            ..::.|   ..:.||..|..|.|:   ..||.:.:.....|   :.|:....|..   |:..|:.
Frog   346 HGDITA---ENIFVNRNDPSEVYL---AGYYFAFRYCPCGK---HVTYREGGRSP---HEGTAEF 398

  Fly   387 KSIATDVKESGHQKLRKKKMCLLIHMLKVALG-----DKLFLKGLQEFFKRYANSSASSKELWEE 446
              |:.|:.:......|.....|...|||...|     ::.....:.|..||:..:.|       |
Frog   399 --ISEDIHKGAAPSRRSDLESLGYCMLKWLCGSLPWSEQTNPNTIMEQKKRFKTNIA-------E 454

  Fly   447 FQRGARRSHQLPTGVS--LPTVME-SWMKQPGFPLL 479
            |...:.:..:.|.|:.  |..||. |:.::|.:.:|
Frog   455 FLGQSFKQRKFPDGLRKYLEYVMNLSYEEKPDYTVL 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	71/357 (20%)
CG6071	NP_648488.1	ERAP1_C	551..929	CDD:288671
vrk3	NP_001037922.1	zinc_ribbon_2	5..27	CDD:379084
vrk3	NP_001037922.1	PKc_like	203..498	CDD:389743	66/333 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900