DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6071 and SON

DIOPT Version :9

Sequence 1:NP_648488.1 Gene:CG6071 / 39308 FlyBaseID:FBgn0036186 Length:962 Species:Drosophila melanogaster
Sequence 2:NP_620305.3 Gene:SON / 6651 HGNCID:11183 Length:2426 Species:Homo sapiens


Alignment Length:453 Identity:83/453 - (18%)
Similarity:144/453 - (31%) Gaps:140/453 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   388 SIATD-------VKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELWE 445
            |:.||       .|...|:|.:.||              |...|..::.:||....|.|..:..:
Human    94 SVQTDPTDEIPTKKSKKHKKHKNKK--------------KKKKKEKEKKYKRQPEESESKTKSHD 144

  Fly   446 E---------FQR-----------------GARRSHQLPTGVSLPTVMESWMKQP---------- 474
            :         |.:                 |...:::.|..|..|.|:...:.:|          
Human   145 DGNIDLESDSFLKFDSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPAT 209

  Fly   475 -----GFPLLTVQRDDAKQIVTITQSRYYQKYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKN 534
                 .....:|..:.::|.|.:.......|.||:.:  ...||...:|...:.|.|. :..:..
Human   210 KTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFA--AAPVPTTTLVLKSSEPVVT-MSVEYQ 271

  Fly   535 SRDILELSHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALRQDFTQ--------IPELSRIQ 591
            .:.:|:.....:||...::.|:..| .:|...|..|.:.||...:.:.:        .||.|.|:
Human   272 MKSVLKSVESTSPEPSKIMLVEPPV-AKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIE 335

  Fly   592 LVDDALSLSWSGRLPYNVTLNVISYLSNETSVLVWE------TALLNLEK--LQSIMRM----TT 644
            .:          ||| ...::|.|.:::.:.....|      |..|.|::  :.|.|.:    .|
Human   336 AL----------RLP-EQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPAT 389

  Fly   645 GFRIFKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTKSPV----------TTESSGTTESP-- 697
            .       |.:|..|.....|......|....|:|....:||          ..|..|.:.:|  
Human   390 S-------MPELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVP 447

  Fly   698 --------------------DTTESPDTAES----PDTTESSNTTESPDTTESSDTTESPDTT 736
                                :..|.|..|:.    |..|.:....|.|..|.:.:.||.|.||
Human   448 QLSQELPGLPAPSMGLEPPQEVPEPPVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPVTT 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6071NP_648488.1 GluZincin 25..477 CDD:301352 21/136 (15%)
ERAP1_C 551..929 CDD:288671 48/242 (20%)
SONNP_620305.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..56
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 77..155 14/74 (19%)
PHA03247 <170..460 CDD:223021 55/311 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..328 3/22 (14%)
PHA03379 <340..673 CDD:223066 35/179 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 406..442 7/35 (20%)
17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM 726..895
MSCRAMM_SdrC <730..903 CDD:380146
11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP] 912..988
14 X 6 AA repeats of [ED]-R-S-M-M-S 1006..1126
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1144..1236
3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG] 1147..1179
rne <1289..1481 CDD:236766
4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT 1359..1390
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1645..1722
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1754..2054
7 X 7 AA repeats of P-S-R-R-S-R-[TS] 1925..1994
2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S 1934..2013
3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R 2013..2039
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2200..2220
G-patch 2305..2349 CDD:396249
DSRM_SF 2369..>2419 CDD:412133
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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