DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6071 and wdr33

DIOPT Version :9

Sequence 1:	NP_648488.1	Gene:	CG6071 / 39308	FlyBaseID:	FBgn0036186	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001362197.1	Gene:	wdr33 / 548794	XenbaseID:	XB-GENE-6083684	Length:	1598	Species:	Xenopus tropicalis

Alignment Length:	125	Identity:	31/125 - (24%)
Similarity:	51/125 - (40%)	Gaps:	35/125 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   575 EALRQDFTQIPELSRIQLVDDALSLSWSGR----------LPYNVTLNVISYLSNETSVLVWETA 629
            :|.||.|.:.|:.::.|.:.   .|::.|:          :.||.  :||.||.|.    ||:..
Frog    20 QAPRQLFYKRPDYAQQQAMQ---QLTFDGKRMRKAVNRKTIDYNP--SVIKYLENR----VWQRD 75

  Fly   630 LLNLEKLQSIMRMTTGFRIFKLYMQKLIEP--AFKTTLNSLSTK-ARTGSEIPINTKSPV 686
            ..::..:|.    ..|      |...|:.|  .....||:::|| .||.:.   ..|.||
Frog    76 QRDMRAIQP----DAG------YYNDLVPPIGMINNPLNAVTTKFVRTSTN---KVKCPV 122

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352
CG6071	NP_648488.1	ERAP1_C	551..929	CDD:288671	31/125 (25%)
wdr33	NP_001362197.1	WD40	121..402	CDD:238121	2/2 (100%)
		WD40 repeat	122..159	CDD:293791	1/1 (100%)
		WD40 repeat	165..200	CDD:293791
		WD40 repeat	205..241	CDD:293791
		WD40 repeat	248..285	CDD:293791
		WD40 repeat	291..328	CDD:293791
		WD40 repeat	336..372	CDD:293791
		WD40 repeat	378..402	CDD:293791
		PAT1	<479..>646	CDD:370676
		Med15	566..>973	CDD:312941
		Med15	905..>1265	CDD:312941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910