Protein Alignment CG6071 and CG8774

DIOPT Version :9

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_650274.2
• Gene: CG8774 / 41635
• FlyBaseID: FBgn0038136
• Length: 942
• Species: Drosophila melanogaster
• Alignment Length: 966
• Identity: 198/966 - (20%)
• Similarity: 363/966 - (37%)
• Gaps: 224/966 - (23%)

  Fly    40 EQNQFEGIVSIDIEATQPTRVIYLNSLNITISRQRTWIYRWASGRKIGALQIKRIIKKTSLIKIV 104
            |...|.|...|.|:..:.|..|.|:|..:.|    |.:|  ...|::...:::. .::..:|.:.
  Fly    86 ETGNFTGQQRISIKVVEATNQIILHSYLLDI----TSVY--VLNREVEKFELEE-ERQFLIITLT 143

  Fly   105 IELPLRSGEIYTLNMLFSGNLDRSQQYGYFAGYY------DKTPRVFYSATRLEPDYAHTVFPCF 163
            .||.:.:.  .||.::|.|.: :.:..|.::..|      .:|    .|.|:.||.||...||||
  Fly   144 EELAVDAS--ITLGIIFGGQM-KDKLVGLYSSTYLNEAGATRT----ISTTKFEPTYARQAFPCF 201

  Fly   164 DDPRFRTPYNITLVH-DRKYVALSNMPPVEEKPYKEIENYVSTTFMGSPPLAT------------ 215
            |:|..:..:.||:|| ...|.|:|||...|.   ..:.:|....|..|..::|
  Fly   202 DEPAMKATFAITVVHPSGSYHAVSNMQQTES---NYLGDYTEAIFETSVSMSTYLVCIIVSDFAS 263

  Fly   216 ---------------QQVMWTLHQLEKVYSGPAAAGENITVWSRPHLAEKLAKVPEMTPNLFSKY 265
                           .|...|.||:.|| ......|:.:|.:...:.     |||
  Fly   264 QSTTVKANGIGEDFSMQAYATSHQINKV-EFALEFGQAVTEYYIQYY-----KVP---------- 312

  Fly   266 ETLFAYPLPKGADWGGKVDHVVLPRYTEMYSGQ----GIMVYGE-----DIVDSGQNGLESLQET 321
                 |||.       |:|...:|.:.   ||.    |::.|.|     |...|.....:|:..|
  Fly   313 -----YPLT-------KLDMAAIPDFA---SGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGT 362

  Fly   322 LAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHLSKTRLDVLYHDSLAKV 386
            ||..:|.||.|.||.::..::.::..|...|       |..:..|..|.....|:.....:|..|
  Fly   363 LAHEIAHQWFGNLVTMKWWNDLWLNEGFARY-------MQYKGVNAVHPDWGMLEQFQIVALQPV 420

  Fly   387 KSIATDVKESGHQKLRK----------------KKMCLLIHMLKVALGDKLFLKGLQEFFKRYAN 435
              :..|.|.|.|..::|                :|...:|.||:..:|.:.|.:.:..:..::..
  Fly   421 --LLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQF 483

  Fly   436 SSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRDDAKQIVTITQSR---- 496
            ::..:.:...|.:       .:.|.:.:..:|.:|.:|.|:|:|.|.: .|.....:||.|
  Fly   484 NNTVTDDFLTEVE-------AVVTDLDIKKLMLTWTEQMGYPVLNVSK-VADGSFKVTQQRFLSN 540

  Fly   497 ---YYQKYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKN---SRDILELSHIANPED--WLLI 553
               |.:...|::....|.||:.:...:         |.:.:   ..|:..:. ||.|.:  |:.:
  Fly   541 PASYEEAPSDSAYGYKWSVPITWFADD---------GSENSFIYDYDVDSVG-IAVPSEVQWIKL 595

  Fly   554 NVDAAVPLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLS 618
            ||:.....||.|:.....|:.:.|.....:.....|..|::||.:|:.:.:|.|.:.|::.:||:
  Fly   596 NVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLA 660

  Fly   619 NETSVLVWETALLNLEKLQSIMRMTTGFRIFKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTK 683
            .|...:.|..|...|..|...:..:.|:..:..|.:.||...::
  Fly   661 QERDFVPWYVASNKLRSLHRSLMFSEGYVSYLTYARSLIAGVYE--------------------- 704

  Fly   684 SPVTTESSGTTESPDTTESPDTAESPDTTESSNTTESPDTTESSDTTESPDTTKSDLSLSAILYR 748
                                                     |...|.::.:..|:.|.:|  :..
  Fly   705 -----------------------------------------EVGWTVDADNHLKNRLRVS--ILT 726

  Fly   749 LACQFEIKECLTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRNGL-EVHWIMVRDMFFESEND 812
            .||...:.:||..|.:||...::..::...| ::||||...|::... :..|..:..:|....:.
  Fly   727 AACALGVPDCLQQASERFSTFLENPTTRPSP-DLREIVYYYGMQQSTSQSSWDQLFQLFVAETDA 790

  Fly   813 KERSILLNSLSCTTEYWAMQKLLSWALDSKKVPRTMT-ASLLSAVLRSPLGYYVGKQFLIDHSKE 876
            .|:..|:..||.......:...|:.|...:.:.|:.. .:.:..:..:|:|..|..:|..:...:
  Fly   791 SEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQ 855

  Fly   877 I-----LRSKDV-KLILTPFIN-AMSTKAEFSALNDHLHRNLPSSMVSGLSSTLES 925
            :     |.:::. :||.....| |.|.|.|..   .|.....|.| .:|.:|.||:
  Fly   856 LTTRFGLNNRNFGRLIAQITANFASSVKLEEV---QHFFSKYPES-GAGANSRLEA 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	108/495 (22%)
		ERAP1_C	551..929	CDD:288671	72/384 (19%)
CG8774	NP_650274.2	Peptidase_M1	67..454	CDD:279741	96/424 (23%)
		M1_APN_2	75..518	CDD:189008	108/495 (22%)
		ERAP1_C	593..910	CDD:288671	72/384 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462037
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850