DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6071 and VB0395L.1

DIOPT Version :9

Sequence 1:	NP_648488.1	Gene:	CG6071 / 39308	FlyBaseID:	FBgn0036186	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_001024932.1	Gene:	VB0395L.1 / 3564909	WormBaseID:	WBGene00044150	Length:	340	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	79/356 - (22%)
Similarity:	131/356 - (36%)	Gaps:	89/356 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLKILVLFCTLLSAKLAES---------FVKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEATQP 57
            ::.:.|:|.:||:..:..|         ...|..||:.:......|....::.|.:.:|..|...
Worm    29 IIYVFVVFGSLLNKTVLPSNNVPSTIPYITVPSEYNVFLQFNSTPEAVVREYTGSLQMDFVARDI 93

  Fly    58 TRVIY--------LNSLNI-----TISRQRTWIYRWASGRKIGALQIKRIIKKTSLIKIVIELP- 108
            |:.::        :||:::     |::......|..::|                 ::..|.|.
Worm    94 TQQLFFHRSDKVKINSISLEDANGTMTAPTAGAYDKSTG-----------------VQAYIPLAN 141

  Fly   109 LRSGEIYTLNMLFSGNLD------RSQQYGYFAGYYDKTPR---VFYSATRLEPDYAHTVFPCFD 164
            |.|.|.|.|.:.|.|.||      |:.||....|    |.|   ||.::........: :.||.|
Worm   142 LTSQESYVLRIDFQGELDSETGSPRNLQYSLPNG----TIRYSIVFGNSVTSSSGLRY-LMPCLD 201

  Fly   165 DPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIEN---YVSTTFMGSPPLATQQVMWTLHQLE 226
            .|.|...:|..:.|..:|..:||..       .:|:.   |.:|.|.||..|.:.||:..|...|
Worm   202 SPDFPAVFNFNIRHSPRYRVISNFA-------GQIQQSILYTATLFAGSFQLDSSQVVLALIDTE 259

  Fly   227 KVYSGPAAAGEN---ITVWSRPHLAEKLAKVPEMTPNLFSKYETLFAYPLPKGADWGGKVDHVVL 288
               ..|....:|   |..:.|..:.:.::     |..:.....|        .:...||:|.:.|
Worm   260 ---LAPVTVQQNGLTINKYYRQSIVDNIS-----TDRIIQFMAT--------RSQQIGKIDVLAL 308

  Fly   289 PRYTEMYSGQGIMVYGE-DI----VDSGQNG 314
            |..|.... .||..|.| |:    ||.|..|
Worm   309 PDLTATQQ-PGITFYNENDVLRENVDLGSLG 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	73/324 (23%)
CG6071	NP_648488.1	ERAP1_C	551..929	CDD:288671
VB0395L.1	NP_001024932.1	GluZincin	63..>224	CDD:301352	39/182 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900