DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6071 and Rnpep

DIOPT Version :9

Sequence 1:	NP_648488.1	Gene:	CG6071 / 39308	FlyBaseID:	FBgn0036186	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_663392.2	Gene:	Rnpep / 215615	MGIID:	2384902	Length:	650	Species:	Mus musculus

Alignment Length:	349	Identity:	68/349 - (19%)
Similarity:	134/349 - (38%)	Gaps:	69/349 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 FPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEK-PYKEIENYVSTTFMGSPPLATQQVMWTLH 223
            |||||.|..:..|:..:.....:.|:.:....|:: |.|..       |..|.|:.:..:...:.
Mouse   179 FPCFDTPAVKCTYSALIEVPDGFTAVMSADTWEKRGPNKFF-------FQMSHPIPSYLIALAIG 236

  Fly   224 QLEKVYSGPAAAGENITVWSRPHLAEKLAK-----VPEMT--------PNLFSKYETLFAYPLPK 275
            .|.....||.:     .||:.|.|.|...:     :.|..        |.::.:|:.||   :|.
Mouse   237 DLASAEVGPRS-----RVWAEPCLIEAAKEEYSGVIEEFLATGEKLFGPYVWGRYDLLF---MPP 293

  Fly   276 GADWGGKVDHVVLPRYTEMYSGQGIMVYGEDIVDSGQNGLESLQETLAELVARQWNGLLVNLEDS 340
            ...:|| :::..|...|.      .::.|:          .||.:.:...::..|.|.||...:.
Mouse   294 SFPFGG-MENPCLTFVTP------CLLAGD----------RSLADVIIHEISHSWFGNLVTNANW 341

  Fly   341 DEEYVRNGINYYLSVQVMA-MDKEAYNTTHLSKTRLDVLYHDSLA---------KVK-SIATDVK 394
            .|.::..|...|...::.. :...||.....:..|..:..|.:::         :|| ....|..
Mouse   342 GEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMNVSGEENPLNKLRVKIEPGVDPD 406

  Fly   395 ESGHQKLRKKKMCLLIHMLKVALGDK----LFLKGLQEFFKRYANSSASSKELWEEFQRGARRSH 455
            ::.::...:|..|.:.::..: :||:    .|||...:.||..:..:....|.:.|:....::.
Mouse   407 DTYNETPYEKGYCFVSYLAHL-VGDQDQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKK- 469

  Fly   456 QLPTGV-SLPTV-MESWMKQPGFP 477
                || |:|.. .:.|:..||:|
Mouse   470 ----GVDSIPGFEFDRWLNTPGWP 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	67/347 (19%)
CG6071	NP_648488.1	ERAP1_C	551..929	CDD:288671
Rnpep	NP_663392.2	leuko_A4_hydro	24..634	CDD:274120	68/349 (19%)
		M1_LTA4H	24..484	CDD:189006	65/342 (19%)
		Substrate binding. /evidence=ECO:0000250	298..302		2/4 (50%)
		Leuk-A4-hydro_C	504..644	CDD:286244
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845899
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830