Protein Alignment CG6071 and AC3.5

DIOPT Version :9

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1079
• Identity: 226/1079 - (20%)
• Similarity: 407/1079 - (37%)
• Gaps: 290/1079 - (26%)

  Fly    22 VKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEATQPTRVIYLNSLNITISRQRTWIYRWASGRKI 86
            |:|:.|::::..::|.    |...|:..:.:...:||..|.||:.:|..:            |.:
 Worm   160 VQPVWYDVSLSPKVGG----NGTMGLAHVKLNIEEPTNKIVLNAKDIEFT------------RNL 208

  Fly    87 GALQIKRIIKKTSLIKI------VIELPLRSGE-------------------------IYTLNML 120
            ..:|:.:.:.|.:...:      ..|:|..|||                         |...|:.
 Worm   209 EKIQLSKEVTKRAKKSVDSGTNSTSEMPEGSGEEAMATTATTTTTESTTPVSSFVDTGIKVTNIE 273

  Fly   121 FSGNLDR-------------------------SQQYGYFAGYYDKTPRVFYSATRLEPDYAHT-- 158
            |..||::                         |...|.....|..:.....|....:|.|::.
 Worm   274 FDENLEKVTLTLDQELKKGSTVVLKIPFTSKVSNNNGLKEYKYKNSEGKEQSMFTTQPSYSYLRH 338

  Fly   159 VFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTFMGSPPLATQQVMWTLH 223
            |||.||...|:.|..|||:|.:..:.::|             ..|.|...|....:|
 Worm   339 VFPSFDQEAFKAPAAITLMHSKGSIVVAN-------------TGVKTKDDGDAQTST-------- 382

  Fly   224 QLEKVYS-----GPAAAGE-------NITVWSRPHLAEKLAK--------VPEMTPNLFSKYET- 267
             |.||..     |...|.|       .|.:|:||.:.....:        :..|...|.|:.|:
 Worm   383 -LNKVLDPDFVIGDLVASEVNTTSGITIRIWTRPEVKHSTEQSLDYANQAIDAMEHILQSRLESK 446

  Fly   268 ---LFAYPLPKGADWGGKV--DHVVLPRYTEMYSGQGIMVYGEDIVDSGQNGLESLQETLAELVA 327
               :.|.|   |...|.:|  ..:|||....:|:.|     ..||     |....:...::..:|
 Worm   447 SLDIVAVP---GFQTGNRVSPSFIVLPEEDILYNEQ-----SNDI-----NQKTRIARMISNRIA 498

  Fly   328 RQWNGLLVNLEDSDEEYVRNGINYYLSVQ----VMAMDKEAYNTTHLSKTRLDVLYHDSLA---- 384
            .||.|.:.|.|:....::...:..:|.|:    ::.::.:...|..:.|    :|..|:.|
 Worm   499 AQWFGGITNPEEFGTFWLNEALPRFLEVEALEKILDINSDDLWTYEMEK----ILERDATATSQP 559

  Fly   385 -KVKSI--ATDVKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELWEE 446
             :||::  :.|:.|..|:.:.||...:| .|::.::|..:|.|.::.|...|.::......||:.
 Worm   560 LRVKNVFSSADIAEIDHEFIGKKGAAVL-RMIQKSVGVNVFNKAIRSFVSSYRSAYPYDDGLWKS 623

  Fly   447 FQR--GARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQR-DDAKQIVTITQSRYYQ--------- 499
            |::  |.:........:.:...:.:|:.|.||||::|:: ||  :.|.::|.|:..
 Worm   624 FEKALGGKLKGWNNEPLDVAKFVNTWVDQIGFPLVSVEKLDD--ETVELSQERFKNDHKTKEQFK 686

  Fly   500 ----KYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKNSRDILELSHIA-----NPEDWLLINV 555
                ||..|     |.||: ::..:..:..|.||             |.|     |..|.:.:|.
 Worm   687 FRNAKYWFN-----WEVPL-FLKSSGPVGNVSWL-------------HEAFRLPLNTSDSIYLNT 732

  Fly   556 DAAVPLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNE 620
            |:....||.|:......|::.|.:...::.|.:|.:|:.|..:|:.||.||:...|||.|||..|
 Worm   733 DSNGVYRVNYEEKRWNDIAKQLEKSHGKLSERTRARLISDVFALANSGALPFETALNVTSYLPME 797

  Fly   621 TSVLVWETALLNLEKLQSIMRMTTGFRIFKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTKSP 685
            |:.:.|..|.                ||||...::|.....:..|||...:       .|:.|..
 Worm   798 TATVPWLIAT----------------RIFKKLTERLEGAPIQDKLNSFIYQ-------KIHKKFE 839

  Fly   686 VTTESSGTTESPDTTESPDTAESPDTTESSNTTESPDTTESSDTTESPDTTKSDLSLSAIL---Y 747
            ..:.|.|..                   |||..::.......|........||:..|:.:.   :
 Worm   840 EISSSPGEA-------------------SSNYLKNRLYANLLDLMAIVKPEKSNEKLNELFVEGF 885

  Fly   748 RLACQFE---IKECLTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRNGLEVHWIMVRDMFFES 809
            ...|||.   ..:|                 |.:|.::||.|.|.|:..|.:..:..||::..:.
 Worm   886 LAPCQFSGNFSSDC-----------------SEVPGDLREKVYCNGVEFGNDTVFETVRELAEKE 933

  Fly   810 ENDKERSILLNSLSCTTEYWAMQKLLSWALDSKKVPRTMTASLLSAVLRS-PLGYYVGKQFLIDH 873
            .:..|:.:|.|||:|..:..|:::|:...|:|     |.|.:||...:.| |:|..:...::||:
 Worm   934 VDGAEKDLLQNSLACFRDPRALRRLILDNLNS-----TSTVTLLLRKMNSRPVGKEIATNWIIDN 993

  Fly   874 SKEILRSK------------DVKLILTPFINAMSTKAEFSALNDHLHRNLPSSMVSGLSSTLESG 926
            ...:|:.|            |..:||    :....|:......:|.|::  :..:..|...:|..
 Worm   994 WSTVLKKKFKNDPETLNAIADAGIIL----DNEREKSMIETFMEHHHKS--THGIESLDKKIEEA 1052

  Fly   927 LDRVNWRNNLYFDLLKAIRDFTLD---DGPKNSSDSDSN 962
            ...:.||.    ..:..:.|: ||   .||....:.:|:
 Worm  1053 TTDIYWRK----QKINELNDY-LDGKMKGPAKDDEMESS 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	106/548 (19%)
		ERAP1_C	551..929	CDD:288671	88/396 (22%)
AC3.5	NP_001256214.1	Peptidase_M1	156..574	CDD:279741	90/468 (19%)
		GluZincin	165..656	CDD:301352	106/546 (19%)
		ERAP1_C	728..1052	CDD:288671	88/393 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020