Protein Alignment CG6071 and pam-1

DIOPT Version :10

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001023210.1
• Gene: pam-1 / 177528
• WormBaseID: WBGene00003914
• Length: 948
• Species: Caenorhabditis elegans
• Alignment Length: 758
• Identity: 174/758 - (22%)
• Similarity: 305/758 - (40%)
• Gaps: 150/758 - (19%)

  Fly    20 SFVKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEATQPTRVIYLNSLNITISRQRTWIYRWASGR 84
            :|.:|..||:    ||.....|..|:|..:||:...:.|.|:.:::.::
 Worm    82 TFAEPTHYNV----RLSPCLNQFSFDGHATIDVTIKEATDVLKVHAQSL---------------- 126

  Fly    85 KIGALQIKRIIKKTSLIK-------------------IVIELP-LRSGEIYTLNMLFSGNLDRSQ 129
                     :|:..|||.                   :.|:|| ....:...|:..|.|.|:...
 Worm   127 ---------LIQSVSLITQPGDASKSLETSYDDKLNILTIKLPTTMQPQKVQLDFKFVGELNDKM 182

  Fly   130 QYGYFAGYYDKT-PRVFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEE 193
            :..|.:.|.||. ...|.::|:.|..||...|||||:|.::..:::||..:....|||||..:.|
 Worm   183 RGFYRSQYKDKNGTEKFLASTQFESTYARYAFPCFDEPIYKATFDVTLEVENHLTALSNMNVISE 247

  Fly   194 KPYKEIENYVSTTFMGSPPLATQQVMWTLHQLEKVYSGPAAAGENITVWSRPHLAEKLAKVPEMT 258
            .|..:.:. .:.||..||.:::..|.:.:.:||.: |....:|..:.|::.|...|:.....:::
 Worm   248 TPTADGKR-KAVTFATSPKMSSYLVAFAVGELEYI-SAQTKSGVEMRVYTVPGKKEQGQYSLDLS 310

  Fly   259 PNLFSKYETLF--AYPLPKGADWGGKVDHVVLPRYT-EMYSGQGIMVYGED--IVDSGQNGLESL 318
            ......|...|  .||||       |.|.:.:|.:: ......|::.|.|.  :||.|.......
 Worm   311 VKCIDWYNEWFDIKYPLP-------KCDLIAIPDFSMGAMENWGLVTYREIALLVDPGVTSTRQK 368

  Fly   319 QE---TLAELVARQWNGLLVNLE-----------DSDEEYVRNGIN--------YYLSVQVMA-M 360
            ..   .:|..:|..|.|.||.::           .|..||:..|.|        ::|:.::.: |
 Worm   369 SRVALVVAHELAHLWFGNLVTMKWWTDLWLKEGFASFMEYMFVGANCPEFKIWLHFLNDELASGM 433

  Fly   361 DKEAYNTTHL------SKTRLDVLYHDSLAKVKSIATDVKESGHQKLRKKKMCLLIHMLKVALGD 419
            ..:|...:|.      :...||.:| ||:...||.:.:                  .||...|.:
 Worm   434 GLDALRNSHPIEVEIDNPNELDEIY-DSITYAKSNSVN------------------RMLCYYLSE 479

  Fly   420 KLFLKGLQEFFKRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTV-QR 483
            .:|.|||:.:.||:..|:|.:::||......        :|.::..:|..|.:|.|||:|.| ||
 Worm   480 PVFQKGLRLYLKRFQYSNAVTQDLWTALSEA--------SGQNVNELMSGWTQQMGFPVLKVSQR 536

  Fly   484 DDA-KQIVTITQSRYYQKYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKNSRDILELSHIANP 547
            .|. .:|:|:.|.|:.....::..|..|.||:...|.: :...|:.....|..:....:..:| |
 Worm   537 QDGNNRILTVEQRRFISDGGEDPKNSQWQVPITVAVGS-SPSDVKARFLLKEKQQEFTIEGVA-P 599

  Fly   548 EDWLLINVDAAVPLRVFYDSYNLQLISEALRQDFT--QIPELSRIQLVDDALSLSWSGRLPYNVT 610
            .:|:.:|.......||.|....|    .|:..|..  ::|.|.|..|::|..:|..:||:.....
 Worm   600 GEWVKLNSGTTGFYRVEYSDEML----TAMLPDIASRRMPVLDRFGLINDLSALLNTGRVSIAQF 660

  Fly   611 LNVISYLSNETSVLVWETALLNLEKLQSIMR-------MTTGFRIFKLYMQKLIEPAF------- 661
            :.|.:..:.|...:||......:.||.:..|       .:....:.|::.|...|..|
 Worm   661 VQVAASSAKEDEYVVWGAIDEGMSKLLACAREMSEDTLKSAKQLVVKMFEQTGAELGFAEQAGED 725

  Fly   662 --KTTLNSL--STKARTGSEIPINTKSPVTTE--SSGTTESPD 698
              |..|.||  :..||.|.:..|:..:.:..:  ..||...||
 Worm   726 SQKMMLRSLVQARLARAGHQPTIDKFTQMFNDFLEKGTPIHPD 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	111/501 (22%)
		ERAP1_C	550..930	CDD:463368	39/171 (23%)
		SSP160	691..>749	CDD:115579	4/8 (50%)
pam-1	NP_001023210.1	M1_APN-Q_like	87..524	CDD:341064	111/501 (22%)
		ERAP1_C	602..927	CDD:463368	39/171 (23%)