Protein Alignment CG6071 and Y67D8C.9

DIOPT Version :10

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001122826.1
• Gene: Y67D8C.9 / 177088
• WormBaseID: WBGene00022073
• Length: 1144
• Species: Caenorhabditis elegans
• Alignment Length: 989
• Identity: 221/989 - (22%)
• Similarity: 377/989 - (38%)
• Gaps: 238/989 - (24%)

  Fly    21 FVKPLRYNLTILTRLGSEDEQNQFE------GIVSIDIEATQPTRVIYLNSL----------NIT 69
            ::.|..|:|.:        :.:||:      ..:||.:|:       |.||.          ||.
 Worm   185 YILPYHYDLQL--------DFSQFDTHLFIRANISIHLES-------YGNSTEDEIQFHLGPNIK 234

  Fly    70 ISRQRTWIYRWASGRKIGALQIKRIIKKTSLIKIVIELPLRSGEIYTLNMLFSGNLDRSQQYGYF 134
            :.|.|.    ...|:|..|...||...| .|.:|.:..||:.|: |.|.|.::..:......|..
 Worm   235 MERMRL----RKDGKKFYAKTFKREESK-KLGRISLRDPLQKGK-YILEMTYNMTICDEDVDGVR 293

  Fly   135 AGYYDKTP---RVFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPY 196
            ....::|.   :.....|:.||..|...|||:|:|..:..:||::.|::||..||||||||...:
 Worm   294 CSLDNQTNSSLKATSFTTKFEPTLARAFFPCWDEPGVKATFNISVRHNKKYTVLSNMPPVESHDH 358

  Fly   197 KEIENYVSTT-FMGSPPLATQQVMWTLHQLEKVYSGPAAAGENITVWSRPHLAEKLAKVPEMTPN 260
            |..|:...|| |..:||::|..:.:.:.:..|:.| ....|..:|||:.|.....:....|..|.
 Worm   359 KSWEDQFKTTVFQTTPPMSTYLLAFAIGEFVKLES-RTERGIPVTVWTYPEDVMSMKFTLEYAPV 422

  Fly   261 LFSKYETL--FAYPLPK-----------GA--DWGGKVDHVVLPRYTEMYSGQGIMVYGEDIVDS 310
            :|.:.|..  ..|||||           |.  :||     :|:..:..:.....|..:..:.||.
 Worm   423 IFDRLEDALEIPYPLPKVDLIAARNFHVGGMENWG-----LVVFEFASIAYTPPITDHVNETVDR 482

  Fly   311 GQNGLESLQETLAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHLSKTRL 375
            ..|... :.:.:|...|.||.|.||.:.|..|.::..|...:...::|:.::..  |....
 Worm   483 MYNEFR-IGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFATFYVYEMMSTERPV--TAQFE---- 540

  Fly   376 DVLYHDSLAK--------------VKSIATD--VKESGHQKLRKKKMCLLIHMLKVALGDKLFLK 424
               |:||||.              |:.:||:  |:.|.|......|.|:||.||:..:.|..|..
 Worm   541 ---YYDSLASLILAQSEEDHRLSLVRELATESQVESSFHPTNLYTKGCVLIRMLRDLVSDFDFKA 602

  Fly   425 GLQEFFKRYANSSASSKELWEEF----QRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRDD 485
            .::.:.::.|..|.|..:|:...    ..||.:.       .|..|:|.|....|.|.:|:.|:.
 Worm   603 AVRRYLRKNAYRSVSRDDLFASLPAYADHGAEQE-------KLSHVLEGWFVNEGIPEITLIRNY 660

  Fly   486 AKQIVTITQSR-----------------------------------------YYQKYLD------ 503
            ..:::||:|.:                                         |.:|..|
 Worm   661 DNEMMTISQRKTVHHEYRSFLKDRKASASVRYRGSRSAEDGSTLFDDALFDGYIEKKKDRRRKHR 725

  Fly   504 ---------------------------NSSNDCWWVPVAYIVRNLTLPQVE-----WLGCQKNSR 536
                                       .:|.|.|.:|:.|:..:|...:.:     ||..:..|.
 Worm   726 PIRRKTSTPPSISPISRRDELRKPRRVGASQDLWTIPITYMFGSLKTSEGQVIREFWLKNRTVSF 790

  Fly   537 DILELSHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDA---LS 598
            ...|:|    |...:|:|.:...|.||.||..|.:|::..|.|:..:|.|.||:||:.||   ||
 Worm   791 GDAEIS----PNQAVLVNPEWKYPYRVNYDLLNWKLLARTLHQNHLEINEKSRMQLILDAEYFLS 851

  Fly   599 LSWSGRLPYNVTLNVISYLSNETSVLVWETALLNLEKLQSIMRMTTGFRIFKLYMQKLIEPAFKT 663
            .|.:..|    .|.::.||::||.:.|....:..:.|...:.:.|...:...:|.:.:|. ....
 Worm   852 NSVNPHL----YLYLLGYLAHETKMEVMLFGIDAVYKFIDVYKATQLNKAILVYFEPVIS-QMDH 911

  Fly   664 TLNSLSTKARTGSEIPIN----TKSPVTTESSGTTESPDTTESPDTAESPDT-TESSNT------ 717
            .||.....|.|.|...:.    .|......::|.:...:...:...:.|||. ||..:.
 Worm   912 LLNESQVDAETASLWLVRPERLAKLYQMRCAAGLSSCKNDYYTQRWSRSPDEWTEDVHKQVTAVC 976

  Fly   718 ----TESPDTTESSDTTESPDTTKSDLSLSAILYRLACQFEIKECLTDAQQRFQAAMDQKSSSSI 778
                |.:||..::..     |...|.|..|...:.|..|  :..|..|.:      :.::::.:|
 Worm   977 HQLFTNTPDEVKTVQ-----DLLDSRLQSSGAKWALTVQ--LAACSHDQK------LLRRTARAI 1028

  Fly   779 PEEIREIVLCRGIRNGLEVH---------WIMVRDM-FFE-----SENDKE----RSILLNSLSC 824
            ......:|....:::...:|         |..:..| .||     |.|..:    ..|||:|:..
 Worm  1029 VSTKNAVVYASALQSDFSLHYNPTFRKYLWAEIAKMSTFEKTALFSTNSTDILPASRILLHSVKT 1093

  Fly   825 TTEYWAMQKLL-SW 837
            ..|...::.|| :|
 Worm  1094 IDELQQIRGLLTNW 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	125/501 (25%)
		ERAP1_C	550..930	CDD:463368	73/326 (22%)
		SSP160	691..>749	CDD:115579	13/68 (19%)
Y67D8C.9	NP_001122826.1	M1_APN-Q_like	190..645	CDD:341064	124/498 (25%)