Protein Alignment CG6071 and AgaP_AGAP002508

DIOPT Version :9

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: XP_312430.5
• Gene: AgaP_AGAP002508 / 1273453
• VectorBaseID: AGAP002508
• Length: 1057
• Species: Anopheles gambiae
• Alignment Length: 1105
• Identity: 244/1105 - (22%)
• Similarity: 422/1105 - (38%)
• Gaps: 264/1105 - (23%)

  Fly     2 LLKILVLFCTLLSAKLAE---------SFVKPLRYNLTILTRLGSE---DEQNQFEGIVSIDIEA 54
            ||....||.::|:...|:         :...|||||:.:.|.:...   |::.:|||.|:|.::.
Mosquito    17 LLLTFFLFLSVLTNSAAQDEQLNYRLPNNTYPLRYNIELTTHIHDNTIGDDRFRFEGKVTIQLKT 81

  Fly    55 T--QPTRVIYLNSLNITISRQRTWIYRWASGRKIGAL--QIKRIIKKTSLIKIVIELPLRSGEIY 115
            .  ..|..:.||...|.|:|.:.| |....|.:...|  ::...:..|... :.:..|......|
Mosquito    82 AGDADTDNVTLNYRRINITRVKLW-YNDQDGWENILLDDELSFTLDSTREF-LTVHSPKPLNGTY 144

  Fly   116 TLNMLFSGNLDRSQQYGYFAGYYDKTPR--VFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVH 178
            .|.:.::|.| |....|::...|.::..  .:.:.|:..|..|..||||:|:|..|.|..:.::|
Mosquito   145 FLEIKYNGTL-REDNGGFYRSSYSESDGNVQWLATTQFSPTDARHVFPCYDEPGIRAPIALRVIH 208

  Fly   179 DRKYVALSNMPPVEEKPYKEIENYVS----TTFMGSPPLATQQVMWTLHQLEKV----------- 228
            .:.|..|||..|::.:     |:.::    |||..:|.:.:..:...:...::|
Mosquito   209 GKSYSVLSNTIPIDVR-----ESILAGMSITTFPDTPKMPSYLLGIIVSDFKEVSLPNFTAQSAF 268

  Fly   229 -----YSGPAA-----AGENITVWSRPHLAEKLAKVPEMTPNLFSKYETLFAYPLPKGADWGGKV 283
                 .:.|.|     ||..|..:     .|:..:.|.:.|.|:
Mosquito   269 IRATALNAPVADFILEAGFKILQY-----LEEFLETPYILPKLY--------------------- 307

  Fly   284 DHVVLPRYT----EMYSGQGIMVYGED--IVDSGQNGLESLQETLAELVARQ------------- 329
             ||.:|.::    |.|   |::.|.|:  :.|...:.::. ::.:|.:|..:
Mosquito   308 -HVAIPDFSPGAMENY---GLITYKEENFMFDPDTSPMKQ-KKKIASIVGHEIGHHYFGNYVSPA 367

  Fly   330 -WNGLLVNLEDSDEEYVRNGINYYLSVQV----------MAMDK--EAYNTTHLSKTRLDVLYHD 381
             |:.|.:.     |.:.|  ...|.:.|:          ..:||  ..:....|..||....|.:
Mosquito   368 WWSYLWMK-----EGFAR--FFEYTAAQIAFPELTIGKMYTVDKTHNVFQLDALGSTRPMTFYVN 425

  Fly   382 SLAKVKSIATDVKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANS-SASSKELWE 445
            |..::.:|..|:...        |...::.||..|.|.:.|.:.:..|.  :.|: .|.:.|.:.
Mosquito   426 SQVEISNIFDDIAYD--------KGGAVLLMLYHAFGKEPFRQAMVNFL--HVNALQAGTPEKFA 480

  Fly   446 EFQRGARRSHQLPTG--VSLPTVMESWMKQPGFPLLTVQRDDAKQIVTITQSRYYQKYLDNSSND 508
            :..:....|...||.  .:..::::||.:|.|:|:|.|.|.|....:.|.|.|:..|..|.|:..
Mosquito   481 QSMQQTMFSSIPPTDPPFNALSLLKSWTEQAGYPILHVSRSDDNCSLRIEQERFLLKSTDASNAT 545

  Fly   509 CWWVPVAYIVRNLTLPQVE------WLGCQKNSRDILELSHIANP--------EDWLLINVDAAV 559
            ..|: :.|.....|.|..:      |         |::..|:.||        :.|::.|.....
Mosquito   546 STWI-IPYNFATETQPNFDDTTATGW---------IVDKYHVINPTADHSWTCDSWIVFNKQQTG 600

  Fly   560 PLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNETSVL 624
            ..||.||.....||.:||.|:.|.|.|.:|.||:||||:::.:|:|.|.:.|.::.|||.|...|
Mosquito   601 YYRVNYDDELWLLIVKALVQNGTIIHESNRAQLIDDALNIARAGKLAYAIPLQLLRYLSKENDYL 665

  Fly   625 VWETALLNLEKLQSIMRMTTGFRIFKLYMQKLIEPAF---------KTTLNSLSTK-------AR 673
            .|.....||..|.::||.|..:..:..|..:.|||::         :.||....|:       .:
Mosquito   666 PWAALDRNLVVLDNLMRGTDSYDDWHKYCSEFIEPSYVEMGMVTQPQDTLTQRMTREIVINWACK 730

  Fly   674 TGSEIPINTKSPVTTESSGTTESPDTTESPDTAESPDTTES--SNTTESPDTTESSDTTESPDTT 736
            .|||..||:...:..|.:|         :|.....||..|:  .|...................:
Mosquito   731 VGSEACINSTRLMVAEIAG---------NPTKDAEPDLREAIYCNGLRYSAAAVFDSIWRKMQQS 786

  Fly   737 KSDLSLSAILYRLACQFEIKECLTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRN---GLEVH 798
            :..|..|.::..|.|....|.    ..:..|:.:|..:|:...:| ||.|.....||   |||:.
Mosquito   787 QDQLYRSELIRSLGCAENAKL----IAKYLQSTIDTDNSTYFNQE-RERVFIAVFRNSLLGLEMA 846

  Fly   799 WIMVRD------MFFESENDKERSILLNSLSCTTEYWAMQKLLSWALDSKKVPRTMTASLLSAVL 857
            ...:|:      ..:...|...|:|  ||:..|    ..|::.|.|:.:|.  :|:||.|
Mosquito   847 MNFLRENSDRVNELYNKGNFGGRAI--NSIIRT----MAQQITSKAMQTKF--QTLTAEL----- 898

  Fly   858 RSPLGYYVGKQFLIDHSKEILRSKDVKLILTPFINAMSTKAE-----------FSALNDHLHR-- 909
                           |.|..||..|:       :.|:...:|           .:|..|..:|
Mosquito   899 ---------------HEKGFLRESDM-------LQALEYSSENLKWIEEKSVQITAWLDEQYRPT 941

  Fly   910 --NLPS---------------SMVSGLSSTLESGLDRVNWRNNLYFDLLKAIRDFTLDDGPKNSS 957
              .|||               |.|:..|||..:....|:..:|.......|:..|:..:....||
Mosquito   942 TNALPSTTVTTNQTPPPVTTTSTVASPSSTTVTTYSYVSTSSNATVPTTSAVYTFSASENVTTSS 1006

  Fly   958  957
            Mosquito  1007  1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	105/520 (20%)
		ERAP1_C	551..929	CDD:288671	105/434 (24%)
AgaP_AGAP002508	XP_312430.5	Peptidase_M1	41..442	CDD:279741	89/454 (20%)
		M1_APN_2	49..514	CDD:189008	105/520 (20%)
		ERAP1_C	592..914	CDD:288671	93/370 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820