Protein Alignment CG6071 and LOC11175863

DIOPT Version :10

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: XP_003436569.2
• Gene: LOC11175863 / 11175863
• VectorBaseID: AGAMI1_006225
• Length: 996
• Species: Anopheles gambiae
• Alignment Length: 1057
• Identity: 206/1057 - (19%)
• Similarity: 371/1057 - (35%)
• Gaps: 266/1057 - (25%)

  Fly    10 CTLLSAKLAESF----------------VKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEATQPT 58
            ||.|.::|.:..                |.|..|::.|......|.|:..|    :.|...|...
Mosquito    80 CTPLHSQLFDEVDLQSRAQLEEYRLNDDVWPTHYDIEIKPYFEPEPEKEAF----TFDATTTIAV 140

  Fly    59 RVIYLNSLNITISRQRTWIYRWASGRKIGALQIKRIIKKTSLIKIVIELPLRSGEI-----YTLN 118
            .|:..|...|.:.:....:..|...||..::.:.::.:..:....:..|.|:..|:     |.:.
Mosquito   141 TVLKDNVTQIKLHKAHMNVTDWRVMRKSNSMPVGKVNETYNEETQIWTLNLKPSELVKNVEYNIV 205

  Fly   119 MLFSGNLDRSQQYGYFAGYYD-KTPRVFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRK- 181
            :.:.|.::.... |::..|:. ...:|:..:|:.|...|...|||||:||::|.:.:.|  |.|
Mosquito   206 VNYVGRMEEDMG-GFYRSYFKVNGKQVWLGSTQFEQTEARRAFPCFDEPRYKTTFTLKL--DYKP 267

  Fly   182 --YVALSNMPPVEEKPYK------------EIENYVSTTFMGSPPLATQQVMWTLHQLEKVYSGP 232
              |...:|.|.|...|.:            ::..|:....:....|.:..||..|.:.|.:....
Mosquito   268 DEYNVYANTPIVNSVPTRYNRTLASFGITPKMSTYLLAFIVAPYELKSSDVMGVLARPEALNQTD 332

  Fly   233 AAAGENITVWSRPHLAEKLAK------------VPEMTPNLFSKYETLFAYPLPKGA-----DWG 280
            .:..|.:          ||.|            |||:|        .::...:|..|     :||
Mosquito   333 YSVQEGL----------KLLKALGNWVDYPFNSVPEIT--------RMYMAAIPDFAAGAMENWG 379

  Fly   281 GKVDHVVLPRYTEMYSGQGIMVYGEDIVDSGQNGLESLQETLAELVARQWNGLLVNLEDSDEEYV 345
                   |..|.|    ..::...||.....|..:.|:   ::..:|.||.|.||..|..|..::
Mosquito   380 -------LITYRE----SSLLYVEEDATSMQQQRIASI---ISHELAHQWFGNLVTCEWWDVTWL 430

  Fly   346 RNGINYY--------------LSVQVM------AMDKEAYNTTHLSKTRLDVLYHDSLAKVKSIA 390
            ..|...|              |.||.:      ||..:....||   .....:|..:.|.....|
Mosquito   431 NEGFATYFEYFGTALVEPLWELDVQFVVEKLQAAMQTDGSLATH---AMTHTVYTQTQAAAMFDA 492

  Fly   391 TDVKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELWEEF-QRGARRS 454
            ....:.|          :::.||:..|...:|...::|:.|....::|..::|:... :|.|..|
Mosquito   493 ISYNKGG----------VVLRMLEHYLSSDVFQAAIREYVKDRQFATARPEQLFTVLDKRNANAS 547

  Fly   455 HQLPTGVSLPTVMESWMKQPGFPLLTVQRDDAKQIVTITQSRYYQKYLDNSSNDCWWVPVAYIVR 519
                      ..|:.|..||||||:||....  ..||:||.|:.....|......|.:|:.:..:
Mosquito   548 ----------AFMKPWTTQPGFPLVTVTSHG--NGVTLTQKRFIANGTDAEEKLLWPLPITFATK 600

  Fly   520 ----NLTLPQVEWLGCQKNSRDILELSHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALR-Q 579
                ..|.|.:  :..:.::..:..:|.:|    :.::|.......||.||....:.|..||| :
Mosquito   601 ESEFESTTPTI--VSSESHNITLANVSDVA----YFILNNQQVGYYRVNYDEALWEKIGAALRSR 659

  Fly   580 DFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNETSVLVWETALLNLEKLQSIMRMTT 644
            .|..|..|:|.|:|||.|:|:.:..|.|...|:::|||..|.....|..|.             .
Mosquito   660 AFGGIHVLNRAQIVDDLLNLAKADVLGYGKVLDLLSYLKQEMEYAPWLAAF-------------N 711

  Fly   645 GF------------RIFKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTKSPVTTESSGTTESP 697
            ||            ::|..|:..::...::.                :..::|
Mosquito   712 GFASLAPRIHPDDEKLFTQYLMDILTDVYEY----------------VKFQAP------------ 748

  Fly   698 DTTESPDTAESPDTTESSNTTESPDTTESSDTTESPDTTKSDLSLSAILYRL----ACQFEIKEC 758
                                                  |:.|..|...|.||    .|::...:|
Mosquito   749 --------------------------------------TQYDRRLHTYLRRLVLDWTCRYGHDDC 775

  Fly   759 LTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRNGLEVHWIMVRDMFFESENDKERSILLNSLS 823
            ...|.:.|:...........| ::|::|.|.|:|.|....:..:.::|..:....|:.:.|..:|
Mosquito   776 SKSAVKEFERFRTNPGVKVHP-DLRQVVYCEGVRKGSSEQFDFLLNIFLTTNVATEQQLTLFGMS 839

  Fly   824 CTTEYWAMQKLLSWALDSKKVPRTMTASLLSAVLRSPLGYYVGKQFLIDHSKEILRS----KDVK 884
            |..:...:.|.:: .:.|..|.....||.||.:|.:.........:|:.||.....:    :.|.
Mosquito   840 CAPKEETVNKFMN-LVSSADVRSQDKASALSMLLNNQHALEPAASYLVQHSARWAEAHGGYRHVA 903

  Fly   885 LILTPF---INAMSTKAEF----SALNDHLHRNLPSSMVSGLSSTLESGLDRVNWRNNLYFDLLK 942
            :.|...   :|.:|.:...    .|..|.|.|.        ....:.:||.:.::..|...:..:
Mosquito   904 MALGGILGRVNDVSVRTSIEQFAEASKDVLGRE--------AYELIAAGLMQFDYNQNFTMNHRE 960

  Fly   943 AIRDFTLDDGPKNSSDS 959
            .||.|........:|::
Mosquito   961 EIRGFLSQKAGSGASET 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	99/505 (20%)
		ERAP1_C	550..930	CDD:463368	76/407 (19%)
		SSP160	691..>749	CDD:115579	4/57 (7%)
LOC11175863	XP_003436569.2	None