Protein Alignment CG6071 and Rnpepl1

DIOPT Version :9

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_852070.3
• Gene: Rnpepl1 / 108657
• MGIID: 1914170
• Length: 720
• Species: Mus musculus
• Alignment Length: 675
• Identity: 128/675 - (18%)
• Similarity: 224/675 - (33%)
• Gaps: 184/675 - (27%)

  Fly   125 LDRSQQYGYFAGYYDKTPRVFYSATRLEPDYAHTV-----FPCFDDPRFRTPYNITLVHDRKYVA 184
            ||....||      :..|.||        ...|:|     |||||.|..:..|:..:   :..:.
Mouse   175 LDPELTYG------NAKPFVF--------TQGHSVCNRSFFPCFDTPAVKCTYSAVV---KAPLG 222

  Fly   185 LSNMPPVEEKPYKEIENYVSTTFMGSPPLATQQVMWTLHQLEKVYSGPAAAGENITVWSRPHLAE 249
            :..:....:..|.|.|....  |....|:....|......|:     ||..|....||:.|.|
Mouse   223 VQVLMSATQSVYVEEEGLYH--FHMEHPVPAYLVALVAGDLK-----PADIGPRSRVWAEPCL-- 278

  Fly   250 KLAKVPEMTPNL-------FSKYETLFAYPLPKGADWGGKVDHVVLPRYTEMYSGQG-IMVYGED 306
                :|..|..|       .|..|.|:      |....|:.|.|.||....:.:.:. .:.:
Mouse   279 ----LPTATSKLSGAVEQWLSAAERLY------GPYMWGRYDIVFLPPSFPIVAMENPCLTF--- 330

  Fly   307 IVDSGQNGLESLQETLAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHLS 371
            |:.|.....|.|...:...||..|.|..|.....:|.::..|:..|...::......|..|...:
Mouse   331 IISSILESDEFLVIDVIHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLET 395

  Fly   372 KTRLDVLYHD----------SLAKVKSIATDVKESGHQKL--RKKKMCLLIHMLKVALGDKLFLK 424
            ..|||.|:..          |..:|| :...|..|....|  .:|..|.:.::.::..|.:.|..
Mouse   396 AFRLDALHRQMRLLGEDSPVSKLQVK-LEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGGPQRFDD 459

  Fly   425 GLQEFFKRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRDDAKQI 489
            .|:.:.::|..:|..:::|.:.|........:...........|.|:...|.||   ...|..|.
Mouse   460 FLRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPL---AEPDLSQG 521

  Fly   490 VTITQSRYYQKYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKNSRDI---------LELSHIA 545
            .::|:                  ||..:.:..|...:|......::.||         |.|..:.
Mouse   522 SSLTR------------------PVEALFQLWTAEPLEQAAASASAIDISKWRTFQTALFLDRLL 568

  Fly   546 N----PED----------WLLINVDAAVPLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDA 596
            :    |::          .||.:::|.:.:|.      ||::   :|.|:  .|:|.|::
Mouse   569 DGSPLPQEVVMSLSKCYSSLLDSMNAEIRIRW------LQIV---VRNDY--YPDLHRVR----- 617

  Fly   597 LSLSWSGRLPYNVTLNVISYLSNETSVLVWETALLNLEKLQSIMRMTTGFRIFKLYMQKLIEPAF 661
                              .:|.::.|                           ::|...|.|...
Mouse   618 ------------------RFLESQMS---------------------------RMYTIPLYEDLC 637

  Fly   662 KTTLNSLSTKA--RTGSEIPIN---TKSPVTTESSGTTESPDTTESPDTAESPDTTESSNTTESP 721
            ...|.|.:.:.  :|...:..|   |...:.::..|.:..|.|..|.|...:...|       :|
Mouse   638 TGALKSFALEVFYQTQGRLHPNLRRTIQQILSQGLGPSAEPSTEPSTDLGGAEADT-------NP 695

  Fly   722 DTTESSDTTESPDTTKS--DLSLSA 744
            |:.......|:|.:|.|  |:::||
Mouse   696 DSPALLLGDEAPSSTISLRDVNVSA 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	78/376 (21%)
		ERAP1_C	551..929	CDD:288671	36/201 (18%)
Rnpepl1	NP_852070.3	M1_LTA4H	29..507	CDD:189006	77/371 (21%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:P15144	321..325		0/3 (0%)
		Leuk-A4-hydro_C	524..668	CDD:312599	31/222 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	671..708		9/43 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845906
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830