Protein Alignment CG32091 and ABCG5

DIOPT Version :10

• Sequence 1: NP_729728.1
• Gene: CG32091 / 39307
• FlyBaseID: FBgn0052091
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_071881.1
• Gene: ABCG5 / 64240
• HGNCID: 13886
• Length: 651
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 153/614 - (24%)
• Similarity: 264/614 - (42%)
• Gaps: 146/614 - (23%)

  Fly    22 YTVKER-KNFWRVTG-----ERRILNGVSGSFRNGQLSAIMGPSGAGKSSLLNAISGFRRDGVTG 80
            |:|..| :.:|.:|.     .|:||..||....:||:..|:|.||:||::||:|:||  |.|..|
Human    45 YSVSHRVRPWWDITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG--RLGRAG 107

  Fly    81 N-----------IKMKRDNAC--YITQDDHHQTLLTVEELMNLACDLKLKNRH-----KKAEIMT 127
            .           ::.::...|  |:.|.|...:.|||.|.::....|.::..:     ||.|.
Human   108 TFLGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEA-- 170

  Fly   128 DILENLHLNHRRNVTAEKLSG---------GERKRLSIALELVDNPNIFFLDEPTSGLDEVTAAQ 183
             ::..|.|:|    .|::|.|         |||:|:|||.:|:.:|.:...||||:|||.:||.|
Human   171 -VMAELSLSH----VADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQ 230

  Fly   184 CIRLLQAMAYEGRTIVCTIHQPSATIYNYFDSIYVLAKGQCVYQGSPRATIPFLRLAQLDCPRHY 248
            .:.||..:|...|.:|.|||||.:.::..||.|.:|:.|:.::.|:|...:.|.......||.|.
Human   231 IVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHS 295

  Fly   249 SPSDYIIELVDAEDGHLVPALSDLTENGKLIYVVSQSEQLAPQQAVTTMFLEQQKRPFLPAFFAG 313
            :|.|:.::|...:                     :||::...:.:.....:|
Human   296 NPFDFYMDLTSVD---------------------TQSKEREIETSKRVQMIE------------- 326

  Fly   314 SAASTDGTLIGGTSALLEQVKAFSKRLHT------DRRDVCG-FRQFIVLMRIMLLRITRARLAL 371
             :|.....:...|...:|::    |.|.|      ..:|..| |.:..||:|.:...:.|.:||:
Human   327 -SAYKKSAICHKTLKNIERM----KHLKTLPMVPFKTKDSPGVFSKLGVLLRRVTRNLVRNKLAV 386

  Fly   372 TIQLFHHLLCGLFFGLIFFQLGNQGARMFDHLKFCIGAVLMIV----YTQVMVPILSYPAEVKLV 432
            ..:|..:|:.|||  |:||.|..:...:...::..:|.:...|    ||.::..:..:|....:.
Human   387 ITRLLQNLIMGLF--LLFFVLRVRSNVLKGAIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVS 449

  Fly   433 KKET----FNRWYTLTPYYMALTVSRLPVQVLLNITFMAVTYWMSGLPQQFWRFCIFVAVGLMIS 493
            .:|:    :.:|..:..|  ||.|  ||..|:..:.|.:|.||..||..:..||..|.|
Human   450 DQESQDGLYQKWQMMLAY--ALHV--LPFSVVATMIFSSVCYWTLGLHPEVARFGYFSA------ 504

  Fly   494 LVAEGMGLAIGATFSITNGSVVGPMLIAPLMGLAVYGFDFAPQVSGGMQLLMKFSYVRVG----- 553
                               :::.|.||...:.|.:.|....|.:...:..|:..:.|.||
Human   505 -------------------ALLAPHLIGEFLTLVLLGIVQNPNIVNSVVALLSIAGVLVGSGFLR 550

  Fly   554 ------VVSLVLAVFGFQREELDCDAIYC 576
                  :...:::.|.||:        ||
Human   551 NIQEMPIPFKIISYFTFQK--------YC 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32091	NP_729728.1	3a01204	30..620	CDD:273361	150/605 (25%)
ABCG5	NP_071881.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32
		ABCG_White	50..275	CDD:213201	76/233 (33%)
		3a01204	60..645	CDD:273361	148/599 (25%)