Protein Alignment CG32091 and Abcg4

DIOPT Version :10

• Sequence 1: NP_729728.1
• Gene: CG32091 / 39307
• FlyBaseID: FBgn0052091
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 633
• Identity: 211/633 - (33%)
• Similarity: 351/633 - (55%)
• Gaps: 53/633 - (8%)

  Fly     2 EQSQNLLAKQSKNVEFQDVYYTVKERKNFWRVTGERRILNGVSGSFRNGQLSAIMGPSGAGKSSL 66
            ::..:|..:.:.::||.::.|:|:|.. .||..|.:.:|..:||.|...:|..||||||||||:.
Mouse    48 QRFSHLPKRSAVDIEFVELSYSVREGP-CWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTF 111

  Fly    67 LNAISGFRRDGVTGNIKMK---------RDNACYITQDDHHQTLLTVEELMNLACDLKLKNRHK- 121
            :|.::|:|..|:.|.|.:.         |..:|||.|||.....|||.|.|.::.:|||..:.:
Mouse   112 MNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEV 176

  Fly   122 KAEIMTDILENLHLNHRRNVTAEKLSGGERKRLSIALELVDNPNIFFLDEPTSGLDEVTAAQCIR 186
            |.|::|:||..|.|....:.....||||:||||:||||||:||.:.|.||||||||..:..|.:.
Mouse   177 KKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 241

  Fly   187 LLQAMAYEGRTIVCTIHQPSATIYNYFDSIYVLAKGQCVYQGSPRATIPFLRLAQLDCPRHYSPS 251
            |::::|:.|||::||||||||.::..||.:|:|::|||:::|.....||:|:...|.||.:::|:
Mouse   242 LMKSLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPA 306

  Fly   252 DYIIELVDAEDGHLVPALSDLTENGKLIYVVSQSEQLAPQQAVTTMFLEQQKRP---FLPAFFAG 313
            |:|||:...|.|.|.|.|....:||                 :.|| .|::..|   .|||....
Mouse   307 DFIIEVASGEYGDLNPMLFRAVQNG-----------------LCTM-AEKKSSPGKNELPAHCPT 353

  Fly   314 SAASTDGTLIGGTSALLEQVKAFSKRLHTDRRDVCGFRQFIVLMRIMLLRITRARLALTIQLFHH 378
            ....            |:.:::.:....|       ..||.:|.|...|.|.|..:...::...|
Mouse   354 CPPE------------LDPIESHTFATST-------LTQFCILFRRTFLSILRDTVLTHLRFMSH 399

  Fly   379 LLCGLFFGLIFFQLGNQGARMFDHLKFCIGAVLMIVYTQVMVPILSYPAEVKLVKKETFNRWYTL 443
            :|.|:..||::..:|:..:::|::..|...::|.:::..:|..:|::|.|:.:..:|..|.||||
Mouse   400 VLIGVLIGLLYLHIGDDASKVFNNTGFLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTL 464

  Fly   444 TPYYMALTVSRLPVQVLLNITFMAVTYWMSGLPQQFWRFCIFVAVGLMISLVAEGMGLAIG-ATF 507
            ..||:|.|::.:|.||:..:.:.::.|||:|.|.:..||.:|.|:.:..:|||:.:||.|| |:.
Mouse   465 KAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAAST 529

  Fly   508 SITNGSVVGPMLIAPLMGLAVYGFDFAPQVSGGMQLLMKFSYVRVGVVSLVLAVFGFQREELDCD 572
            |:...:.|||:...|::..:.:...| ..:...:|.....||||.|...|:|.::|.:|..|.|.
Mouse   530 SLQVATFVGPVTAIPVLLFSGFFVSF-KTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCL 593

  Fly   573 AIYCHFSDPRVLLKFLDVEKVSMLHQFGLLAMLMLFFRVMMYISLRKR 620
            ...|.|.||:::|:.||||:..:...|.:|.:..|..|::.|:.||.|
Mouse   594 DEQCPFRDPQIILRELDVEEAKLYMDFLVLGIFFLALRLLAYLVLRYR 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32091	NP_729728.1	3a01204	30..620	CDD:273361	204/603 (34%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	211/633 (33%)