Protein Alignment PCID2 and PCID2

DIOPT Version :10

• Sequence 1: NP_648486.1
• Gene: PCID2 / 39306
• FlyBaseID: FBgn0036184
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001307585.1
• Gene: PCID2 / 55795
• HGNCID: 25653
• Length: 453
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 201/446 - (45%)
• Similarity: 274/446 - (61%)
• Gaps: 55/446 - (12%)

  Fly     4 TVNNYLSGVLHAAQDLDGESLATYLSLRDVHVQNHNLYIAQPEKLVDRFLKPPLDEVVSAHLKVL 68
            |:|.||..|..|....||.|.|..:|.:..||.|..|.:|.||:...:.|:||.||:.:|||:..
Human     5 TINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCT 69

  Fly    69 Y----H-----------LAQEPPGYMEAYTQQS--------------AACG-------------- 90
            |    |           :.|.|..:|.|...::              |:|.
Human    70 YAVGNHDFIEAYKCQTVIVQYPLSFMAAVPHRTHAVDYLGLETRKHWASCSFLQLERNDSVLEQK 134

  Fly    91 ---------AVVRLLQQLKDENWCLPLMYRVCLDLRYLAQACEKHC--QGFTP-GHVLEKAADCI 143
                     :.:|..|..|:|||.||:||.|.||||..|...::..  :|.:. |.:|||||:.:
Human   135 LVSALSLGTSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELL 199

  Fly   144 MACFRVCAADGRASEEDTKRLGMMNLVNQLFKIYFRINKLHLCKPLIRAIDNCIFKDSFPLPEQI 208
            |:||||||:|.||..||:|:.||:.||||||||||:|||||||||||||||:...||.:...:::
Human   200 MSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRV 264

  Fly   209 TYKYFVGRRAMFDSNYQAAVQYLSYAFSNCPDRFASNKRLILIYLVPVKMLLGYLPSKSLLQRYD 273
            ||||:|||:|||||:::.|.:|||:||.:|......|||:|||||:|||||||::|:..||::|.
Human   265 TYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYH 329

  Fly   274 LLLFLDLAMAMKAGNVNRFDEIVRDQELVLIRSGIYLLVEKLKFLVYRNLFKKVFVIRKSHQLDM 338
            |:.|.::..|:..||:....|.:...|...||.||:|::||||.:.||||||||:::.|:|||.:
Human   330 LMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSL 394

  Fly   339 GDFLSALHFVGLTDVSLDETHCIVANLIYDGKIKGYISHAHNKLVVSKQNPFPSVS 394
            ..||.||.|:.:.||.:||..||:|||||.|.:||||||.|.|||||||||||.:|
Human   395 DAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCID2	NP_648486.1	PINT	<136..391	CDD:470471	146/254 (57%)
PCID2	NP_001307585.1	PINT	<190..447	CDD:470471	110/206 (53%)