DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PCID2 and Pcid2

DIOPT Version :9

Sequence 1:	NP_648486.1	Gene:	PCID2 / 39306	FlyBaseID:	FBgn0036184	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001162615.1	Gene:	Pcid2 / 361182	RGDID:	1307041	Length:	399	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	198/394 - (50%)
Similarity:	271/394 - (68%)	Gaps:	5/394 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TVNNYLSGVLHAAQDLDGESLATYLSLRDVHVQNHNLYIAQPEKLVDRFLKPPLDEVVSAHLKVL 68
            |:|.||..|..|....||.|.|..:|.:..||.|..|.:|.||:...:.|:||.||:.:|||:..
  Rat     5 TINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCT 69

  Fly    69 YHLAQEPPGYMEAYTQQSAACGAVVRLLQQLKDENWCLPLMYRVCLDLRYLAQACEKHC--QGFT 131
            |.:...  .::|||..|:....:.:|..|..|:|||.||:||.|.||||..|...::..  :|.:
  Rat    70 YAVGNH--DFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKS 132

  Fly   132 P-GHVLEKAADCIMACFRVCAADGRASEEDTKRLGMMNLVNQLFKIYFRINKLHLCKPLIRAIDN 195
            . |.:|||||:.:|:||||||:|.||..||:|:.||:.||||||||||:|||||||||||||||:
  Rat   133 KVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDS 197

  Fly   196 CIFKDSFPLPEQITYKYFVGRRAMFDSNYQAAVQYLSYAFSNCPDRFASNKRLILIYLVPVKMLL 260
            ...||.:...:::||||:|||:|||||:::.|.:|||:||.:|......|||:|||||:||||||
  Rat   198 SNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLL 262

  Fly   261 GYLPSKSLLQRYDLLLFLDLAMAMKAGNVNRFDEIVRDQELVLIRSGIYLLVEKLKFLVYRNLFK 325
            |::|:..||::|.|:.|.::..|:..||:...:|.:...|...||.||:|::||||.:.||||||
  Rat   263 GHMPTIELLRKYHLMQFSEVTRAVSEGNLLLLNEALAKHETFFIRCGIFLILEKLKIITYRNLFK 327

  Fly   326 KVFVIRKSHQLDMGDFLSALHFVGLTDVSLDETHCIVANLIYDGKIKGYISHAHNKLVVSKQNPF 390
            ||:::.|:|||.:..||.||.|:.:.||.:||..||:||||:.|.|||||||.|.||||||||||
  Rat   328 KVYLLLKTHQLSLDAFLVALKFMHVEDVDIDEVQCILANLIHMGHIKGYISHQHQKLVVSKQNPF 392

  Fly   391 PSVS 394
            |.:|
  Rat   393 PPLS 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PCID2	NP_648486.1	PCI	<136..391	CDD:295179	146/254 (57%)
Pcid2	NP_001162615.1	PCI	80..393	CDD:413200	167/312 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337036
Domainoid	1	1.000	264	1.000	Domainoid score	I1857
eggNOG	1	0.900	-	-		E1_COG5600
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10168
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1940
OMA	1	1.010	-	-		QHG54456
OrthoDB	1	1.010	-	-		D349064at33208
OrthoFinder	1	1.000	-	-		FOG0004189
OrthoInspector	1	1.000	-	-		oto95668
orthoMCL	1	0.900	-	-		OOG6_101860
Panther	1	1.100	-	-	LDO	PTHR12732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770