DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PCID2 and SPAC1B3.08

DIOPT Version :9

Sequence 1:	NP_648486.1	Gene:	PCID2 / 39306	FlyBaseID:	FBgn0036184	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_594792.1	Gene:	SPAC1B3.08 / 2542528	PomBaseID:	SPAC1B3.08	Length:	423	Species:	Schizosaccharomyces pombe

Alignment Length:	423	Identity:	122/423 - (28%)
Similarity:	211/423 - (49%)	Gaps:	49/423 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FGTVNNYL--SGVLHAAQDLD---GESLATYLS--LRDVHVQNHNLYIAQPEKLVDRFLKPPLDE 59
            |.|:|:.:  |..:..|::|.   |::|.:.|:  :...:..:..|.:.     |:|.:.....:
pombe    12 FSTINSAVARSNSVLLAKNLSIPWGKTLTSVLNFDIPGTYSSDDVLKLT-----VERSISKNWTD 71

  Fly    60 VVSAHLKVLYHLAQE-PPGYMEAYTQQSAACGAVVRLLQQLKDENWCLPLMYRVCLDLRYLA--- 120
            :|..||:||.:|.:: .|.  .|:.||:.....:.|.....:.....||:::.||.|||:||
pombe    72 IVLLHLQVLLYLVRDHDPA--AAFKQQTELAQHLYREFSSGRCTGVHLPVLFIVCKDLRFLAINA 134

  Fly   121 ----------------QACEKHCQGFTPGHVLEKAADCIMACFRVCAADGRASEEDTKRLGMMNL 169
                            ...|::.|       ||..|..|...|.:|..| ||....:::.|...:
pombe   135 HNAMLRRKQQLKVISVDESEENEQ-------LEATARLINRAFTICIND-RAPLSTSRKWGAYYI 191

  Fly   170 VNQLFKIYFRINKLHLCKPLIRAIDNCIFKD--SFPLPEQITYKYFVGRRAMFDSNYQAAVQYLS 232
            :..|||:|.|::.:||...::||:......|  .||....:.:.|::|..|..:.||:.|...|.
pombe   192 MGLLFKLYLRLDCVHLTNNVLRAMKVVELPDISLFPKSHVVIFHYYLGIVAFLNQNYKNASAELE 256

  Fly   233 YAFSNCPDRFASNKRLILIYLVPVKMLLGY-LPSKSLLQRYDLL--LFLDLAMAMKAGNVNRFDE 294
            .|||.|...:..|..|||.|.:|.::|:.: ||:|:||.::..|  :::.|..|:|:||:..|.:
pombe   257 IAFSLCHKGYNRNLELILSYWIPTRILVNHQLPTKNLLSKFPNLASVYIPLTRALKSGNLGEFGK 321

  Fly   295 IVRDQELVLIRSGIYLLVEKLKFLVYRNLFKKVFVI-RKSHQLDMGDFLSALHFVGLTDVSLDET 358
            .::..|.:|.::.|||.:|..:.|..||||:|.::| .||.:|.:..|..||...| ||:.....
pombe   322 CLQKNETLLAKTKIYLTLEGTRDLCIRNLFRKTWIICGKSTRLPVSVFQIALQVAG-TDLPKLHV 385

  Fly   359 HCIVANLIYDGKIKGYISHAHNKLVVSKQNPFP 391
            ..|:||:|..|.::||||.....:|:|.::|||
pombe   386 EAILANMISKGYMRGYISRNFETVVLSAKDPFP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PCID2	NP_648486.1	PCI	<136..391	CDD:295179	86/260 (33%)
SPAC1B3.08	NP_594792.1	COG5600	9..423	CDD:227887	122/423 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	87	1.000	Domainoid score	I2146
eggNOG	1	0.900	-	-		E1_COG5600
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10168
Inparanoid	1	1.050	151	1.000	Inparanoid score	I1304
OMA	1	1.010	-	-		QHG54456
OrthoFinder	1	1.000	-	-		FOG0004189
OrthoInspector	1	1.000	-	-		oto100525
orthoMCL	1	0.900	-	-		OOG6_101860
Panther	1	1.100	-	-	LDO	PTHR12732
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R253
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860