Protein Alignment CG6083 and KCNAB2

DIOPT Version :10

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001186791.1
• Gene: KCNAB2 / 8514
• HGNCID: 6229
• Length: 415
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 72/343 - (20%)
• Similarity: 129/343 - (37%)
• Gaps: 97/343 - (28%)

  Fly    10 NGKNMPMLGLGTW-----RSPPEVVTQAVKDAIDIGYRHFDCAHIYG---NEAQVGAALREKMDE 66
            :|..:..||||||     :...|:..|.:..|.|.|...||.|.:|.   .|..:|..:::|
Human    78 SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK--- 139

  Fly    67 GVVTRDELFITSKL-WNTHHKPDL------VRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNL 124
             ...|..|.||:|: |....:.:.      :....:.|:..|.::|:               |.:
Human   140 -GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYV---------------DVV 188

  Fly   125 YPTCPDTNK-------AAFEDIDYV--DTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAK-- 178
            :...||.|.       ::.:...::  :|.|||.:::::|:....|.|.::..::....|||:
Human   189 FANRPDPNTPMEGDPFSSSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQF 253

  Fly   179 --LKPVVLQIECHPYLSQK---PLITLCYDNAIAVTAYSCLG---------SGHTPYEKPG--AY 227
              ..|:..|.|.|.:..:|   .|..|.:...:....:|.|.         ||..||.:..  .|
Human   254 NLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGY 318

  Fly   228 PLLQH--------------PTILAIAEKYERTAAQV----LLRFQTQSGII-------------- 260
            ..|:.              ..:.||||:...|..|:    .||.:..|.::
Human   319 QWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIG 383

  Fly   261 ---VIPR-SVSKQHMLDN 274
               |:|: |.|..|.:|:
Human   384 AIQVLPKLSSSIIHEIDS 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	AKR_SF	4..299	CDD:444925	72/343 (21%)
KCNAB2	NP_001186791.1	Aldo_ket_red_shaker	71..395	CDD:381367	69/335 (21%)