DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and AKR4C11

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_190956.1	Gene:	AKR4C11 / 824555	AraportID:	AT3G53880	Length:	315	Species:	Arabidopsis thaliana

Alignment Length:	275	Identity:	110/275 - (40%)
Similarity:	165/275 - (60%)	Gaps:	20/275 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVT 70
            |.|:.|..:|.:|||||::.|.||..||..|:.|||:|.|||..||||.::|..|::..|:|||.
plant     8 FQLNTGAKIPSVGLGTWQAAPGVVGDAVAAAVKIGYQHIDCASRYGNEIEIGKVLKKLFDDGVVK 72

  Fly    71 RDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS-----DNLYPTCPD 130
            |::||||||:|.|...|..|:.|...::::|.:.|::|||||||:..|.|:     :|:.|
plant    73 REKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLKKGTVDFKPENIMP---- 133

  Fly   131 TNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQK 195
                    ||...||:|||.|||.|..:|||||||:.::::.|:..|::.|.|.|:||||...|.
plant   134 --------IDIPSTWKAMEALVDSGKARAIGVSNFSTKKLSDLVEAARVPPAVNQVECHPSWQQH 190

  Fly   196 PLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGII 260
            .|...|....|.::.||.|||..|.:.|.   .:|:.|.|..||::..::.||..||:..|.|..
plant   191 KLHEFCKSKGIHLSGYSPLGSPGTTWVKA---DVLKSPVIEMIAKEIGKSPAQTALRWGLQMGHS 252

  Fly   261 VIPRSVSKQHMLDNF 275
            ::|:|.::..:.:||
plant   253 ILPKSTNEGRIRENF 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	110/275 (40%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	106/264 (40%)
AKR4C11	NP_190956.1	AKR_AKR4C1-15	6..292	CDD:381351	110/275 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I557
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1036
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm2923
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840