Protein Alignment CG6083 and AKR1D1

DIOPT Version :9

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 128/314 - (40%)
• Similarity: 198/314 - (63%)
• Gaps: 10/314 - (3%)

  Fly     8 LSNGKNMPMLGLGTWRSPPE----VVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGV 68
            ||:|.::|::||||:..|..    ....:||.|||.||||.|.|:||.||.:||.|:|||:.||.
Human    12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGK 76

  Fly    69 VTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNK 133
            |.|:::|...|||.|:|.|::|||..|.::|.|.:.|::||::..|||:|.| |.:||. .:..|
Human    77 VRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPG-DEIYPR-DENGK 139

  Fly   134 AAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQKP 196
            ..:...:...||.|||...|.||.:::||||||.:|:..:|:.  .|.|||..|:|||||.:|..
Human   140 WLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPK 204

  Fly   197 LITLCYDNAIAVTAYSCLGSGHTP-YEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGII 260
            |:..|..:.|.:||||.||:...| :....:.|||:...:.::.::|.:||||::|||..|.|::
Human   205 LLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVV 269

  Fly   261 VIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            |||:|.:.:.:.:|| :|:||.|..::::.|..|:.|.||:.:.....||.:||
Human   270 VIPKSFNLERIKENF-QIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	122/298 (41%)
		Tas	17..293	CDD:223739	116/282 (41%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	124/309 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830