DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and akr1a1

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001016137.1	Gene:	akr1a1 / 548891	XenbaseID:	XB-GENE-1014353	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	143/318 - (44%)
Similarity:	216/318 - (67%)	Gaps:	15/318 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKM--DEGVVT 70
            |..|:.:|::|||||:|.|..|..|||.|:.:||||.|||.:||||.:||.|::|.:  |:| ::
Frog    10 LYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDKG-LS 73

  Fly    71 RDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAA 135
            |:|:|:||||||..|.||.|..|...::::|.:.||:|||||||.|:|.| |.::|..|| ....
Frog    74 REEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFKRG-DQIFPQNPD-GSVQ 136

  Fly   136 FEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITL 200
            ::..||.|||:|||.||.:||.:|||:||||::|::.::|:|.:||.|||:||||||:|..||..
Frog   137 YDLTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAY 201

  Fly   201 CYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRS 265
            |:.:.:..|.||.|||....:.||....||:.|.|:|:|:||.::.||:|||:|.|..::.||:|
Frog   202 CHAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQRKVVSIPKS 266

  Fly   266 VSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFM---------TMKAAYGHPHHPF 314
            |:...:|.|| :::||.|:.:::|.|..|:.|.|::         ::....|||.:||
Frog   267 VTPTRILQNF-QVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSVPRDAGHPLYPF 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	137/293 (47%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	132/277 (48%)
akr1a1	NP_001016137.1	AKR_AKR1A1-4	10..314	CDD:381332	138/307 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		oto102417
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930