Protein Alignment CG6083 and akr1b1

DIOPT Version :10

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001011130.1
• Gene: akr1b1 / 496546
• XenbaseID: XB-GENE-5821742
• Length: 318
• Species: Xenopus tropicalis
• Alignment Length: 309
• Identity: 142/309 - (45%)
• Similarity: 205/309 - (66%)
• Gaps: 5/309 - (1%)

  Fly     8 LSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRD 72
            |..|..||::|||||:|.|..||.||..||::||||.|||::|.||.:||..:::|:.||:|.|:
 Frog     9 LYTGAQMPIVGLGTWKSEPGKVTAAVAKAIEVGYRHLDCAYVYQNENEVGEGIQQKIKEGLVKRE 73

  Fly    73 ELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFE 137
            :||:.||||:|.|...:|:.||:.::.:|.:.||:|||:|||..:::| |.|:| ..:.......
 Frog    74 DLFVVSKLWSTFHDKSMVKGACQKTLSDLKLDYLDLYLVHWPTGFQAG-DALFP-LDNEGCVIHS 136

  Fly   138 DIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQKPLITL 200
            :..::|||..||.|||.||.:|||:||||.:|:.:||:.  .|.||.|.|.||||||:||.||.|
 Frog   137 NTHFLDTWEGMEELVDAGLVKAIGISNFNREQIEQLLNKPGLKHKPAVHQFECHPYLTQKKLIDL 201

  Fly   201 CYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRS 265
            |....|.|||||.|||...|:.||....||:.|.|..||:||.:|:||||:||..|..::|||:|
 Frog   202 CQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEEPKIKEIAKKYNKTSAQVLIRFHIQRNVVVIPKS 266

  Fly   266 VSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            |:...:.:|| :::||||:.:|.:||...:...|...:.:|..|..:||
 Frog   267 VTPARIEENF-QVFDFELSPEDTEAIFSFERGWRVCALSSAKKHKDYPF 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	AKR_SF	4..299	CDD:444925	137/292 (47%)
akr1b1	NP_001011130.1	AKR_AKR1B1-19	12..318	CDD:381333	141/306 (46%)