Protein Alignment CG6083 and AKR1B15

DIOPT Version :9

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001074007.2
• Gene: AKR1B15 / 441282
• HGNCID: 37281
• Length: 344
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 127/289 - (43%)
• Similarity: 185/289 - (64%)
• Gaps: 5/289 - (1%)

  Fly    29 VTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPA 93
            |.:|||.|||..|||.|||:.|.|:.:||.|::||:.|..|.|::|||.||:|.|..:..|||.|
Human    56 VKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFERPLVRKA 120

  Fly    94 CETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQ 158
            .|.::::|.:.||::||:|||..:|:| |:.:|.....|..:.:. .::|.|.|||.||||||.:
Human   121 FEKTLKDLKLSYLDVYLIHWPQGFKTG-DDFFPKDDKGNMISGKG-TFLDAWEAMEELVDEGLVK 183

  Fly   159 AIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPY 221
            |:||||||..|:.|||:.  .|.|||..|:||||||:|:.||..|:...|.|||||.|||...|:
Human   184 ALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPW 248

  Fly   222 EKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVD 286
            .||....||:.|.|..||.|:::|.||||:||..|..:.|||:|::..|:::|. :::||:|:.:
Human   249 AKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENI-QVFDFKLSDE 312

  Fly   287 DIQAINELDCNGRFMTMKAAYGHPHHPFE 315
            ::..|...:.|.|....|........||:
Human   313 EMATILSFNRNWRAFDFKEFSHLEDFPFD 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	123/272 (45%)
		Tas	17..293	CDD:223739	122/265 (46%)
AKR1B15	NP_001074007.2	ARA1	56..325	CDD:223729	123/271 (45%)
		Tas	57..317	CDD:223739	120/262 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158407
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.860