DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and Akr1c12

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001014262.3	Gene:	Akr1c12 / 364773	RGDID:	1359406	Length:	323	Species:	Rattus norvegicus

Alignment Length:	316	Identity:	115/316 - (36%)
Similarity:	190/316 - (60%)	Gaps:	15/316 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LSNGKNMPMLGLGTWRSPPEV----VTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGV 68
            |::|..:|.||.||:: |.||    ..:|...|||:||||.|.|..|..|.::|.|::.|:..||
  Rat    10 LNDGHFIPALGFGTYK-PKEVPKSKSLEAAHLAIDVGYRHIDTASAYQVEEEIGQAIQSKIKAGV 73

  Fly    69 VTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNK 133
            |.|.::|||:|||.:..:.::||||.|.|::||.:.|::|:|:|:|:..||..|.    .|...|
  Rat    74 VKRKDMFITTKLWCSCFRTEMVRPALEKSLKNLQLDYVDLFLIHYPVPIKSSVDE----SPLDEK 134

  Fly   134 AAF--EDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQ 194
            ..|  :.:|:.|||..:|...|.||.::|||||||.:|:.|||:.  .|.|||..|:|||.||:|
  Rat   135 GKFLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQ 199

  Fly   195 KPLITLCYDNAIAVTAYSCLGS-GHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSG 258
            ..|:..|....|.:.||..||: .:..:....:..||..|.:..:|:|.:|:.|.:.||:..|.|
  Rat   200 SKLLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLDDPILCDVAKKNKRSPALIALRYLFQRG 264

  Fly   259 IIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            ::.:.:|..:..|.:|. ::::|:|:.:|::.::.|:.|.|:::.:....||.:||
  Rat   265 VVPLAQSFKENEMRENL-QVFEFQLSPEDMKTLDGLNKNFRYLSAEFLADHPEYPF 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	110/300 (37%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	105/284 (37%)
Akr1c12	NP_001014262.3	ARA1	8..305	CDD:223729	110/300 (37%)
Akr1c12	NP_001014262.3	Tas	16..297	CDD:223739	106/286 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352397
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860