DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and Akr1c19

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001094046.1	Gene:	Akr1c19 / 307096	RGDID:	1562954	Length:	323	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	120/314 - (38%)
Similarity:	196/314 - (62%)	Gaps:	11/314 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LSNGKNMPMLGLGTWRSPPEV----VTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGV 68
            |::|..:|.||.||:: |.||    ..:|:..|::.|:||.|.|::|..|..||.|::.|:..|:
  Rat    10 LNDGHFIPALGFGTYK-PEEVPENKPLEAIHLAVEAGFRHIDTAYVYQTENHVGQAIKSKIAAGI 73

  Fly    69 VTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNK 133
            |.|:::|||:|||.|.|:|::|..:.|.|::||.:.|::||::|:||..|||.| ::|. .:..|
  Rat    74 VKREDIFITTKLWCTFHRPEMVLSSLEKSLKNLQLDYVDLYIIHYPMQMKSGED-MFPE-DENGK 136

  Fly   134 AAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQKP 196
            ..|:.:|...||.|||...|.||.::|||||||.:|:.::|:.  .|.|||..|:|||.||:|..
  Rat   137 TLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQSK 201

  Fly   197 LITLCYDNAIAVTAYSCLGSGHTP-YEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGII 260
            |:..|....|.:.||..|||.... :..|.:..||..|.:..:|:|::|::||:.||:|.|.|.:
  Rat   202 LLNYCKSRDIVLVAYCALGSQRPKRWVDPSSPVLLNDPVLCDVAKKHQRSSAQIALRYQLQRGNV 266

  Fly   261 VIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            |:.:|..:..:.:|. ::::|||..:|::.::.||.|.|:.......|||.:||
  Rat   267 VLAQSYKENEIKENI-QVFEFELPSEDMKILDSLDRNLRYAPAPFGQGHPEYPF 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	114/298 (38%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	108/282 (38%)
Akr1c19	NP_001094046.1	AKR_AKR1C1-35	6..308	CDD:381334	115/301 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352398
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.760