Protein Alignment CG6083 and Akr1b1

DIOPT Version :10

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_036630.1
• Gene: Akr1b1 / 24192
• RGDID: 2092
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 156/317 - (49%)
• Similarity: 205/317 - (64%)
• Gaps: 21/317 - (6%)

  Fly     8 LSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRD 72
            |:||..||.||||||:|||..||:|||.|||:||||.|||.:|.||.:||.||:||:.|.||.|.
  Rat     7 LNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQ 71

  Fly    73 ELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSD--------NLYPTCP 129
            :|||.||||.|.|...:|:.||:.::.:|.:.||:|||:|||..:|.|.|        |:.|:
  Rat    72 DLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPS-- 134

  Fly   130 DTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYL 192
                    |.|:||||.|||.||||||.:||||||||..|:.|:|:.  .|.||.|.||||||||
  Rat   135 --------DTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYL 191

  Fly   193 SQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQS 257
            :|:.||..|:...|.|||||.|||...|:.||....||:.|.|..||.||.:|.||||:||..|.
  Rat   192 TQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQR 256

  Fly   258 GIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            .::|||:||:...:.:||| ::||||:.:|:..:...:.|.|...:.:...|..:||
  Rat   257 NLVVIPKSVTPARIAENFK-VFDFELSNEDMATLLSYNRNWRVCALMSCAKHKDYPF 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	AKR_SF	4..299	CDD:444925	152/300 (51%)
Akr1b1	NP_036630.1	AKR_AKR1B1-19	10..315	CDD:381333	154/314 (49%)