DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and C07D8.6

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_509242.1	Gene:	C07D8.6 / 180997	WormBaseID:	WBGene00015565	Length:	317	Species:	Caenorhabditis elegans

Alignment Length:	328	Identity:	117/328 - (35%)
Similarity:	177/328 - (53%)	Gaps:	24/328 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDE 66
            :|.:..||||..||::|||||:|.|..|..|||.|:..|||..|.|.:|.||..:|.|::|.::|
Worm     4 ATASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELLEE 68

  Fly    67 GVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDT 131
            |||.|:|||||:|.|.....|..:......|::.|.::|::|||.|.|.|:..          |.
Worm    69 GVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFND----------DM 123

  Fly   132 NKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPV-VLQIECHPYLSQK 195
            ::.....::  |.||..:.:...||.:|:||||:|..|::|.|::. |.|| ..|:|.|.|..|.
Worm   124 SEHIASPVE--DVWRQFDAVYKAGLAKAVGVSNWNNDQISRALALG-LTPVHNSQVELHLYFPQH 185

  Fly   196 PLITLCYDNAIAVTAYSCLGS-GHTPYEKPGAYPL--------LQHPTILAIAEKYERTAAQVLL 251
            ..:..|..:.|:||:|:.||| |...:..|....|        ||...:||:|||..:|.|||||
Worm   186 DHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNVLALAEKTHKTPAQVLL 250

  Fly   252 RFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFEP 316
            |:....|..::|:|:.:..:.:||: ::||.|..:||..:.|...:.|........|||...|..
Worm   251 RYALDRGCAILPKSIQENRIKENFE-VFDFSLTEEDIAKLEESKNSQRLFLQDFMTGHPEDAFAA 314

  Fly   317 KAK 319
            :.|
Worm   315 ERK 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	111/307 (36%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	103/285 (36%)
C07D8.6	NP_509242.1	AKR_AKR1G1_CeAKR	5..301	CDD:381380	112/309 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166067
Domainoid	1	1.000	211	1.000	Domainoid score	I1629
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760