DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and exc-15

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001367925.1	Gene:	exc-15 / 178844	WormBaseID:	WBGene00020369	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	121/324 - (37%)
Similarity:	185/324 - (57%)	Gaps:	15/324 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTPNFLLSNGKNMPMLGLGTWRSPPEV-VTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKM 64
            |:..:..|:.|..:|:.|||||:...|. :|.|::.|:|.|||..|.||:|.||..:|..|.|.:
Worm     1 MTVDSIPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYI 65

  Fly    65 DEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCP 129
            ..|.:.|:::|:||||..|.|.|:.|....|:.::.|.::|::|||:|.|..:|....:..|..
Worm    66 SSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQEGSFAPLM- 129

  Fly   130 DTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQ 194
            :..:.|..:|.::|||||:|.|..||..:|:|||||:..|:..|...|::||...|:|||.|..|
Worm   130 ENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQVECHIYWPQ 194

  Fly   195 KPLITLCYDNAIAVTAYSCLGSGHTPYEK--------PGAYPLLQHPTILAIAEKYERTAAQVLL 251
            :.|..||....:.||||:.|||   |..|        |...|||: |.:..:|.||.:||||:|:
Worm   195 QELRALCKKLGVTVTAYAPLGS---PGRKAARPDGVWPEGDPLLE-PIVKQLAAKYHKTAAQILI 255

  Fly   252 RFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFE 315
            |..||.||..||:|||...:::|.. .:||:|:.:|:..:|.::...|......|..||..|.:
Worm   256 RHLTQHGISTIPKSVSPDRIVENIS-TFDFKLSDEDMHTLNSIETRTRLFIADFAVKHPFFPHD 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	116/307 (38%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	111/284 (39%)
exc-15	NP_001367925.1	AKR_AKR1G1_CeAKR	3..306	CDD:381380	116/308 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.830