Protein Alignment CG6083 and AKR1C2

DIOPT Version :9

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001345.1
• Gene: AKR1C2 / 1646
• HGNCID: 385
• Length: 323
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 130/314 - (41%)
• Similarity: 206/314 - (65%)
• Gaps: 11/314 - (3%)

  Fly     8 LSNGKNMPMLGLGTWRSPPEV----VTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGV 68
            |::|..||:||.||: :|.||    ..:|||.||:.|:.|.|.||:|.||.|||.|:|.|:.:|.
Human    10 LNDGHFMPVLGFGTY-APAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGS 73

  Fly    69 VTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNK 133
            |.|:::|.|||||:..|:|:|||||.|.|::||.:.|::|||:|:|::.|.| :.:.|. .:..|
Human    74 VKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG-EEVIPK-DENGK 136

  Fly   134 AAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQKP 196
            ..|:.:|...||.|||...|.||.::|||||||.:.:..:|:.  .|.|||..|:|||||.:|:.
Human   137 ILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRK 201

  Fly   197 LITLCYDNAIAVTAYSCLGS-GHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGII 260
            |:..|....|.:.|||.||| ...|:..|.:..||:.|.:.|:|:|::||.|.:.||:|.|.|::
Human   202 LLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVV 266

  Fly   261 VIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            |:.:|.::|.:..|. ::::|:|..::::||:.|:.|.|::|:....|.|::||
Human   267 VLAKSYNEQRIRQNV-QVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	124/298 (42%)
		Tas	17..293	CDD:223739	118/282 (42%)
AKR1C2	NP_001345.1	AKR_AKR1C1-35	6..308	CDD:381334	125/301 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.760