DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and Akr1b7

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_038962847.1	Gene:	Akr1b7 / 116463	RGDID:	620257	Length:	329	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	133/286 - (46%)
Similarity:	188/286 - (65%)	Gaps:	9/286 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 RSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKP 87
            ||||..|.:|||.|||.||||||||::|.||::||.|::||:.|..|.|::|||.||||:|..:.
  Rat    35 RSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIKEKAVRREDLFIVSKLWSTFFEK 99

  Fly    88 DLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLV 152
            .|::.|.:.::.:|.:.||:|||:|||...::|.:.| |. ....|.......::|.|..||.||
  Rat   100 SLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGKEFL-PK-DSQGKVLMSKSTFLDAWEGMEELV 162

  Fly   153 DEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLG 215
            |:||.:|:||||||..|:.|||:.  .|.|||..|:||||||:|:.||..|:...|||.|||.||
  Rat   163 DQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLG 227

  Fly   216 SGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWD 280
            |...||.||....:|:.|.|..||.|:::|.||||:||..|..:.|||:||:..|:.:|. :::|
  Rat   228 SPDRPYAKPEDPVVLEIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENI-QVFD 291

  Fly   281 FELAVDDIQAINELDCN----GRFMT 302
            |:|:.:|:.||..|:.|    |.|:|
  Rat   292 FQLSEEDMAAILSLNRNWRACGLFVT 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	131/282 (46%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	128/271 (47%)
Akr1b7	XP_038962847.1	AKR_SF	35..329	CDD:412396	133/286 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352392
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760