DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6083 and Akr1c14

DIOPT Version :9

Sequence 1:	NP_648485.1	Gene:	CG6083 / 39305	FlyBaseID:	FBgn0036183	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_598833.1	Gene:	Akr1c14 / 105387	MGIID:	2145458	Length:	323	Species:	Mus musculus

Alignment Length:	318	Identity:	126/318 - (39%)
Similarity:	197/318 - (61%)	Gaps:	9/318 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TPNFLLSNGKNMPMLGLGTW---RSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKM 64
            :|..:|::|..:|.||.||.   :.|.:.:.:|.|.|||.|:||||.|::|..|.:||.|:|.|:
Mouse     5 SPRVVLNDGHFIPALGFGTTVPDKVPKDELIKATKIAIDTGFRHFDSAYLYQIEEEVGQAIRSKI 69

  Fly    65 DEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCP 129
            ::|.|.|:::|.|||||:|.|:|:|||...|.:::|..:.|::||::|:|||.:.| |.|:|. .
Mouse    70 EDGTVKREDIFYTSKLWSTFHRPELVRSCLEKTLKNAQLDYVDLYIIHFPMALQPG-DKLFPR-D 132

  Fly   130 DTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSV--AKLKPVVLQIECHPYL 192
            :..|...|.:|..|||.|||...|.||.::|||||||.:|:..:|:.  .|.|||..|:|||.||
Mouse   133 EHGKLLAEAVDLCDTWEAMEKCKDAGLAKSIGVSNFNFRQLETILNKPGLKYKPVCNQVECHLYL 197

  Fly   193 SQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYP-LLQHPTILAIAEKYERTAAQVLLRFQTQ 256
            :|..::..|....|.:.:|..|||...........| ||..|.:.|:|.||::|.|.:.:|:|.|
Mouse   198 NQSQMLDYCKSKDIILVSYCTLGSSRDKIWVDQKSPVLLDDPVLCAMANKYKQTPALIAIRYQLQ 262

  Fly   257 SGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPF 314
            .||:|:.||. |:..:..|.::::|:||.:|::.::.|..|.|:.|......||:|||
Mouse   263 RGIVVLTRSF-KEKRIKEFMKVFEFQLASEDMKVLDGLHRNLRYNTASYFDDHPNHPF 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	119/302 (39%)
CG6083	NP_648485.1	Tas	17..293	CDD:223739	113/281 (40%)
Akr1c14	NP_598833.1	AKR_AKR1C1-35	6..308	CDD:381334	120/304 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930