Protein Alignment CG6083 and AKR1A1

DIOPT Version :9

• Sequence 1: NP_648485.1
• Gene: CG6083 / 39305
• FlyBaseID: FBgn0036183
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 147/324 - (45%)
• Similarity: 212/324 - (65%)
• Gaps: 13/324 - (4%)

  Fly     1 MSTPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALREKMD 65
            |:....||..|:.||::|||||:|.|..|..|||.|:.:||||.|||.|||||.::|.||:|.:.
Human     1 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 65

  Fly    66 EG-VVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGSDNLYPTCP 129
            .| .|.|:|||:|||||||.|.|:.|.||...::.:|.::||:|||||||.|::.| ||.:|...
Human    66 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG-DNPFPKNA 129

  Fly   130 DTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQ 194
            | ....::...|.:||:|:|.||.:||.||:|:||||.:|::.:||||.::|.|||:||||||:|
Human   130 D-GTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQ 193

  Fly   195 KPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSGI 259
            ..||..|....:.|||||.|||....:..|....||:.|.:||:||||.|:.||:|||:|.|..:
Human   194 NELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKV 258

  Fly   260 IVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMT---------MKAAYGHPHHPF 314
            |.||:|::...:|.|.| ::||..:.::::.:|.|:.|.|::.         :....|||.:||
Human   259 ICIPKSITPSRILQNIK-VFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6083	NP_648485.1	ARA1	1..300	CDD:223729	141/299 (47%)
		Tas	17..293	CDD:223739	132/276 (48%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	141/299 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		oto88543
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730