Protein Alignment Akr1B and AAD10

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_012689.1
• Gene: AAD10 / 853620
• SGDID: S000003916
• Length: 288
• Species: Saccharomyces cerevisiae
• Alignment Length: 301
• Identity: 56/301 - (18%)
• Similarity: 98/301 - (32%)
• Gaps: 115/301 - (38%)

  Fly   105 REDLFITSKLWNTFHRPDLVKS---------------ALENTLSSLKLKYLDLYLIHWPMGYKEG 154
            |:.:.|.:|....:...|:.|.               ::.::|..|:..::|:..:||
Yeast     7 RDQIVIATKFTTDYKGYDVGKGKSANFCGNHKRSLHVSVRDSLRKLQTDWIDILYVHW------- 64

  Fly   155 CDLFPTDKDGKTLYSPVDYV----DTWKAMEKLVEEGLVKSIGVS-------------------- 195
                            .||:    :...::..||::|.|..:|||
Yeast    65 ----------------WDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKT 113

  Fly   196 ---------NFNRRQIERVLEVATIPPVTNQ--IECHPY-------LTQKKLIDFCKSKDITITA 242
                     |...|..||     .|.|:...  :...|:       ...||.::..|.|
Yeast   114 PFSIYQGKWNVLNRDFER-----DIIPMARHFGMALAPWDVMGGGRFQSKKAVEERKKK------ 167

  Fly   243 YSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPG-----QILIRYQVQRANIVIP----KSV 298
                |...|.:....:...: |.||.|...|..:..|     .|.|.|...:|..|.|    :.:
Yeast   168 ----GEGLRTFFGTSEQTDM-EVKISEALLKVAEEHGTESVTAIAIAYVRSKAKHVFPLVGGRKI 227

  Fly   299 TKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAG 339
              :.::.|.:....:||||:|:.:||      :||.  |.|
Yeast   228 --EHLKQNIEALSIKLTPEQIKYLES------IVPF--DVG 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	56/301 (19%)
AAD10	NP_012689.1	AKR_SF	<1..250	CDD:444925	50/283 (18%)