Protein Alignment Akr1B and AAD4

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_010038.1
• Gene: AAD4 / 851354
• SGDID: S000002402
• Length: 329
• Species: Saccharomyces cerevisiae
• Alignment Length: 334
• Identity: 73/334 - (21%)
• Similarity: 125/334 - (37%)
• Gaps: 103/334 - (30%)

  Fly    53 LGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDE---VGDGVEAKIKEGVVKREDLFITSKL 114
            :|:.|  |.|..|.:....:||...||.|..||||:.   :|:.::::     ..|:.:.|.:|.
Yeast     1 MGSMN--KEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMKSR-----KLRDQIVIATKF 58

  Fly   115 WNTFHRPDL--VKSA-------------LENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDG 164
            ...:.:.::  .|||             :.::|..|:..::|:..:||
Yeast    59 TGDYKKYEVGGGKSANYCGNHKHSLHVSVRDSLRKLQTDWIDILYVHW----------------- 106

  Fly   165 KTLYSPVDYV----DTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPY-L 224
                  .||:    :...::..||::|.|..:|||:.....:......||....|      |: :
Yeast   107 ------WDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKT------PFSI 159

  Fly   225 TQKKL----IDFCKSKDITITAYSPLGSPNRPW-----------------AKAGDPVIL------ 262
            .|.|.    .||  .:|| |......|....||                 .|.|:.:..
Yeast   160 YQGKWNVLNRDF--ERDI-IPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTVSGTSK 221

  Fly   263 ---EEAKIKEIAAKKKKTPG-----QILIRYQVQRANIVIP----KSVTKDRIESNFQVFDFELT 315
               :|.||.|..||..:..|     .|.|.|...:|..|.|    :.:  :.::.|.:....:||
Yeast   222 QTDKEVKISEALAKVAEEHGTESVTAIAIAYVRSKAKNVFPLVGGRKI--EHLKQNIEALSIKLT 284

  Fly   316 PEEIEIIES 324
            ||:||.:||
Yeast   285 PEQIEYLES 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	66/324 (20%)
		Tas	45..>248	CDD:223739	46/221 (21%)
AAD4	NP_010038.1	AKR_AKR9A3_9B1-4	1..292	CDD:381373	71/331 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345901
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930