Protein Alignment Akr1B and AAD3

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_010032.1
• Gene: AAD3 / 850471
• SGDID: S000000704
• Length: 363
• Species: Saccharomyces cerevisiae
• Alignment Length: 335
• Identity: 75/335 - (22%)
• Similarity: 124/335 - (37%)
• Gaps: 76/335 - (22%)

  Fly    60 KGQVTEAVKVAIDAGYRHIDCAYVYQNEDE---VGDGVEA-KIKEGVVKREDLFITSKLW----- 115
            |.:..|.:....:||...||.|...|||..   :|:.::: ::::.:|.......:.|.:
Yeast    49 KNRAFELLDTFYEAGGNFIDAANNCQNEQSEEWIGEWIQSRRLRDQIVIATKFIKSDKKYKAGES 113

  Fly   116 NTF-----HRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTD-----KDGKTLYSP 170
            ||.     |:..|..| :.::|..|:..::|:..:|| ..|....:.|...     :.||.||..
Yeast   114 NTANYCGNHKRSLHVS-VRDSLRKLQTDWIDILYVHW-WDYMSSIEEFMDSLHILVQQGKVLYLG 176

  Fly   171 VDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQ-----IERVLEVATIPPVTN-QIECHPY------ 223
            |.....|...   .......|.|.:.|:..|     :.|..|...||...: .:...|:
Yeast   177 VSDTPAWVVS---AANYYATSYGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGG 238

  Fly   224 -LTQKKLIDFCKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPG-----QIL 282
             ...||.::..:.....|.::  :|:..:..|         |.||.|..||..:..|     .|.
Yeast   239 RFQSKKAMEERRKNGEGIRSF--VGASEQTDA---------EIKISEALAKIAEEHGTESVTAIA 292

  Fly   283 IRYQVQRANIVIPKSVTKDRIE---SNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAG----- 339
            |.|...:|....| ||...:||   .|.:....:|||:.|:.:||      :||.  |.|
Yeast   293 IAYVRSKAKNFFP-SVEGGKIEDLKENIKALSIDLTPDNIKYLES------IVPF--DIGFPNNF 348

  Fly   340 ------THKY 343
                  |.||
Yeast   349 IVLNSLTQKY 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	75/335 (22%)
AAD3	NP_010032.1	AKR_AKR9A3_9B1-4	17..335	CDD:381373	66/302 (22%)