DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akr1B and AT5G62420

DIOPT Version :9

Sequence 1:	NP_001261716.1	Gene:	Akr1B / 39304	FlyBaseID:	FBgn0086254	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_201048.1	Gene:	AT5G62420 / 836363	AraportID:	AT5G62420	Length:	316	Species:	Arabidopsis thaliana

Alignment Length:	309	Identity:	111/309 - (35%)
Similarity:	172/309 - (55%)	Gaps:	15/309 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GNEIPVIGLGTFNSPKGQ--VTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKRED 107
            |..||::|:||:...|.:  ...||..||..||||.|.|.:|.:|:.:|..:...|..|.|:|:|
plant    11 GETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGTVQRDD 75

  Fly   108 LFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVD 172
            ||:|||||::.|...:  |||..||.::.|.|||.||:|||:..|.|.. .|..|:.: ....:.
plant    76 LFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLKPGVS-EPIPKEDE-FEKDLG 136

  Fly   173 YVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCKSKD 237
            ..:||:.||:.:|.||.:|||||||:.::|..:|:.|::.|..||:|.||...|:||...|:..:
plant   137 IEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENN 201

  Fly   238 ITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDR 302
            |.::.|||||.|...|   |...::|...||.||.|...||.|:.:|:.:.:...||.||....|
plant   202 IHVSGYSPLGGPGNCW---GSTAVIEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKSFNGAR 263

  Fly   303 IESNFQVFDFELTPEEIEIIESFE----CNGRLVPLLNQYGHPHHPFEK 347
            :..|.:..:.:|..:::.:|:..|    ..|..  |:||...|:...::
plant   264 MIENKRALEIKLDDQDLSLIDHLEEWKIMRGDF--LVNQTTSPYKSIQQ 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	104/272 (38%)
Akr1B	NP_001261716.1	Tas	45..>248	CDD:223739	83/204 (41%)
AT5G62420	NP_201048.1	AKR_AKR4A_4B	10..288	CDD:381350	105/283 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1036
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm2923
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.940