DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akr1B and AT2G21250

DIOPT Version :9

Sequence 1:	NP_001261716.1	Gene:	Akr1B / 39304	FlyBaseID:	FBgn0086254	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_179721.1	Gene:	AT2G21250 / 816664	AraportID:	AT2G21250	Length:	309	Species:	Arabidopsis thaliana

Alignment Length:	289	Identity:	123/289 - (42%)
Similarity:	179/289 - (61%)	Gaps:	12/289 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLF 109
            |.::|::|||.:...|..:.:.:..||..||||:|||..|:||.||||.:....|.|:|||||||
plant     8 GFKMPIVGLGVWRMEKEGIRDLILNAIKIGYRHLDCAADYRNETEVGDALTEAFKTGLVKREDLF 72

  Fly   110 ITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDK----DG-KTLYS 169
            ||:||||:.|  ..|..|.:::|..|:|.||||:|:|:|:..|. ..:..||.    || ..:.:
plant    73 ITTKLWNSDH--GHVIEACKDSLKKLQLDYLDLFLVHFPVATKH-TGVGTTDSALGDDGVLDIDT 134

  Fly   170 PVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCK 234
            .:....||..|||||..|||:|||:||::.......|..:.|.|..||||.|||..:..|:.||:
plant   135 TISLETTWHDMEKLVSMGLVRSIGISNYDVFLTRDCLAYSKIKPAVNQIETHPYFQRDSLVKFCQ 199

  Fly   235 SKDITITAYSPLG--SPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKS 297
            ...|.:||::|||  :.|..|  .|....|::..:|::|.|.|||..|:::|:.:||..:||||:
plant   200 KHGICVTAHTPLGGATANAEW--FGTVSCLDDPVLKDVAEKYKKTVAQVVLRWGIQRKTVVIPKT 262

  Fly   298 VTKDRIESNFQVFDFELTPEEIEIIESFE 326
            ....|:|.|||||||||:.|::|:|:|.|
plant   263 SKPARLEENFQVFDFELSKEDMEVIKSME 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	118/277 (43%)
Akr1B	NP_001261716.1	Tas	45..>248	CDD:223739	89/209 (43%)
AT2G21250	NP_179721.1	AKR_AKR2A1-2	1..308	CDD:381338	123/289 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H116462
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm1169
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.730